Pavani G - Search Results

1

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.

Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, Liu JH, Clerin V, Pittman DD, Rose-Miranda R, Shields KM, Erbe DV, Tobin JF, Arruda VR, Camire RM. Ivanciu L, et al. Among authors: pavani g. Nat Biotechnol. 2011 Oct 23;29(11):1028-33. doi: 10.1038/nbt.1995. Nat Biotechnol. 2011. PMID: 22020385 Free PMC article.

2

Catalytic domain modification and viral gene delivery of activated factor VII confers hemostasis at reduced expression levels and vector doses in vivo.

Margaritis P, Roy E, Faella A, Downey HD, Ivanciu L, Pavani G, Zhou S, Bunte RM, High KA. Margaritis P, et al. Among authors: pavani g. Blood. 2011 Apr 14;117(15):3974-82. doi: 10.1182/blood-2010-09-309732. Epub 2011 Feb 16. Blood. 2011. PMID: 21325603 Free PMC article.

3

The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.

Pavani G, Ivanciu L, Faella A, Marcos-Contreras OA, Margaritis P. Pavani G, et al. Blood. 2014 Aug 14;124(7):1157-65. doi: 10.1182/blood-2014-04-567297. Epub 2014 Jun 23. Blood. 2014. PMID: 24957146 Free PMC article.

4

Asymmetric processing of mutant factor X Arg386Cys reveals differences between intrinsic and extrinsic pathway activation.

Baroni M, Pavani G, Pinotti M, Branchini A, Bernardi F, Camire RM. Baroni M, et al. Among authors: pavani g. Biochim Biophys Acta. 2015 Oct;1854(10 Pt A):1351-6. doi: 10.1016/j.bbapap.2015.05.012. Epub 2015 May 23. Biochim Biophys Acta. 2015. PMID: 26012870

5

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.

Marcos-Contreras OA, Smith SM, Bellinger DA, Raymer RA, Merricks E, Faella A, Pavani G, Zhou S, Nichols TC, High KA, Margaritis P. Marcos-Contreras OA, et al. Among authors: pavani g. Blood. 2016 Feb 4;127(5):565-71. doi: 10.1182/blood-2015-09-671420. Epub 2015 Dec 23. Blood. 2016. PMID: 26702064 Free PMC article.

6

One amino acid in mouse activated factor VII defines its endothelial protein C receptor (EPCR) binding and modulates its EPCR-dependent hemostatic activity in vivo.

Pavani G, Zintner SM, Ivanciu L, Small JC, Stafford KA, Szeto JH, Margaritis P. Pavani G, et al. J Thromb Haemost. 2017 Mar;15(3):507-512. doi: 10.1111/jth.13607. Epub 2017 Feb 14. J Thromb Haemost. 2017. PMID: 28035745 Free article.

7

Gene-based FVIIa prophylaxis modulates the spontaneous bleeding phenotype of hemophilia A rats.

Zintner SM, Small JC, Pavani G, Dankner L, Marcos-Contreras OA, Gimotty PA, Kjelgaard-Hansen M, Wiinberg B, Margaritis P. Zintner SM, et al. Among authors: pavani g. Blood Adv. 2019 Feb 12;3(3):301-311. doi: 10.1182/bloodadvances.2018027219. Blood Adv. 2019. PMID: 30705032 Free PMC article.

8

Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model.

Borst S, Nations CC, Klein JG, Pavani G, Maguire JA, Camire RM, Drazer MW, Godley LA, French DL, Poncz M, Gadue P. Borst S, et al. Among authors: pavani g. Stem Cell Reports. 2021 Jun 8;16(6):1458-1467. doi: 10.1016/j.stemcr.2021.04.013. Epub 2021 May 20. Stem Cell Reports. 2021. PMID: 34019812 Free PMC article.

9

Membrane binding and anticoagulant properties of protein S natural variants.

Baroni M, Pavani G, Marescotti D, Kaabache T, Borgel D, Gandrille S, Marchetti G, Legnani C, D'Angelo A, Pinotti M, Bernardi F. Baroni M, et al. Among authors: pavani g. Thromb Res. 2010 Feb;125(2):e33-9. doi: 10.1016/j.thromres.2009.09.015. Epub 2009 Oct 29. Thromb Res. 2010. PMID: 19878975

10

Overcoming preexisting humoral immunity to AAV using capsid decoys.

Mingozzi F, Anguela XM, Pavani G, Chen Y, Davidson RJ, Hui DJ, Yazicioglu M, Elkouby L, Hinderer CJ, Faella A, Howard C, Tai A, Podsakoff GM, Zhou S, Basner-Tschakarjan E, Wright JF, High KA. Mingozzi F, et al. Among authors: pavani g. Sci Transl Med. 2013 Jul 17;5(194):194ra92. doi: 10.1126/scitranslmed.3005795. Sci Transl Med. 2013. PMID: 23863832 Free PMC article.

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