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Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.
Chang Q, Jorgensen C, Pawson T, Hedley DW. Chang Q, et al. Among authors: pawson t. Br J Cancer. 2008 Oct 7;99(7):1074-82. doi: 10.1038/sj.bjc.6604676. Epub 2008 Sep 16. Br J Cancer. 2008. PMID: 18797457 Free PMC article.
Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.
Douville EM, Afar DE, Howell BW, Letwin K, Tannock L, Ben-David Y, Pawson T, Bell JC. Douville EM, et al. Among authors: pawson t. Mol Cell Biol. 1992 Jun;12(6):2681-9. doi: 10.1128/mcb.12.6.2681. Mol Cell Biol. 1992. PMID: 1375325 Free PMC article.
Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.
Caron L, Abraham N, Pawson T, Veillette A. Caron L, et al. Among authors: pawson t. Mol Cell Biol. 1992 Jun;12(6):2720-9. doi: 10.1128/mcb.12.6.2720. Mol Cell Biol. 1992. PMID: 1375326 Free PMC article.
To understand the mechanism(s) by which p56lck participates in T-cell receptor (TCR) signalling, we have examined the effects of mutations in known regulatory domains of p56lck on the ability of F505 p56lck to enhance the responsiveness of an antigen-specific murine T
To understand the mechanism(s) by which p56lck participates in T-cell receptor (TCR) signalling, we have examined the effects of muta …
A retrovirus encoding the v-fps protein-tyrosine kinase induces factor-independent growth and tumorigenicity in FDC-P1 cells.
Meckling-Gill KA, Yee SP, Schrader JW, Pawson T. Meckling-Gill KA, et al. Among authors: pawson t. Biochim Biophys Acta. 1992 Oct 6;1137(1):65-72. doi: 10.1016/0167-4889(92)90101-g. Biochim Biophys Acta. 1992. PMID: 1390902
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.
Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T, et al. Rozakis-Adcock M, et al. Among authors: pawson t. Nature. 1992 Dec 17;360(6405):689-92. doi: 10.1038/360689a0. Nature. 1992. PMID: 1465135
Tyrosine kinases and their interactions with signalling proteins.
Pawson T. Pawson T. Curr Opin Genet Dev. 1992 Feb;2(1):4-12. doi: 10.1016/s0959-437x(05)80314-4. Curr Opin Genet Dev. 1992. PMID: 1633425 Review.
Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases.
Ellis C, Moran M, McCormick F, Pawson T. Ellis C, et al. Among authors: pawson t. Nature. 1990 Jan 25;343(6256):377-81. doi: 10.1038/343377a0. Nature. 1990. PMID: 1689011
p185neu is phosphorylated on tyrosine in human primary breast tumors which overexpress neu/erbB-2.
Wildenhain Y, Pawson T, Blackstein ME, Andrulis IL. Wildenhain Y, et al. Among authors: pawson t. Oncogene. 1990 Jun;5(6):879-83. Oncogene. 1990. PMID: 1694290
Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase.
Reith AD, Ellis C, Lyman SD, Anderson DM, Williams DE, Bernstein A, Pawson T. Reith AD, et al. Among authors: pawson t. EMBO J. 1991 Sep;10(9):2451-9. EMBO J. 1991. PMID: 1714377 Free PMC article.
Tyrosine phosphorylation of GAP and GAP-associated proteins in lymphoid and fibroblast cells expressing lck.
Ellis C, Liu XQ, Anderson D, Abraham N, Veillette A, Pawson T. Ellis C, et al. Among authors: pawson t. Oncogene. 1991 Jun;6(6):895-901. Oncogene. 1991. PMID: 1906156
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