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301 results
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Zebrafish modelling of leukaemias.
Payne E, Look T. Payne E, et al. Br J Haematol. 2009 Aug;146(3):247-56. doi: 10.1111/j.1365-2141.2009.07705.x. Epub 2009 May 19. Br J Haematol. 2009. PMID: 19466976 Review.
NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis.
Forrester AM, Grabher C, McBride ER, Boyd ER, Vigerstad MH, Edgar A, Kai FB, Da'as SI, Payne E, Look AT, Berman JN. Forrester AM, et al. Br J Haematol. 2011 Oct;155(2):167-81. doi: 10.1111/j.1365-2141.2011.08810.x. Epub 2011 Aug 2. Br J Haematol. 2011. PMID: 21810091
L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.
Payne EM, Virgilio M, Narla A, Sun H, Levine M, Paw BH, Berliner N, Look AT, Ebert BL, Khanna-Gupta A. Payne EM, et al. Blood. 2012 Sep 13;120(11):2214-24. doi: 10.1182/blood-2011-10-382986. Epub 2012 Jun 25. Blood. 2012. PMID: 22734070 Free PMC article.
Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML.
Payne EM, Bolli N, Rhodes J, Abdel-Wahab OI, Levine R, Hedvat CV, Stone R, Khanna-Gupta A, Sun H, Kanki JP, Gazda HT, Beggs AH, Cotter FE, Look AT. Payne EM, et al. Blood. 2011 Jul 28;118(4):903-15. doi: 10.1182/blood-2010-11-318022. Epub 2011 Jun 7. Blood. 2011. PMID: 21653321 Free PMC article.
L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way.
Narla A, Payne EM, Abayasekara N, Hurst SN, Raiser DM, Look AT, Berliner N, Ebert BL, Khanna-Gupta A. Narla A, et al. Br J Haematol. 2014 Nov;167(4):524-528. doi: 10.1111/bjh.13069. Epub 2014 Aug 7. Br J Haematol. 2014. PMID: 25098371 Free PMC article.
Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish.
Bolli N, Payne EM, Grabher C, Lee JS, Johnston AB, Falini B, Kanki JP, Look AT. Bolli N, et al. Blood. 2010 Apr 22;115(16):3329-40. doi: 10.1182/blood-2009-02-207225. Epub 2010 Mar 2. Blood. 2010. PMID: 20197555 Free PMC article.
cpsf1 is required for definitive HSC survival in zebrafish.
Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT. Bolli N, et al. Blood. 2011 Apr 14;117(15):3996-4007. doi: 10.1182/blood-2010-08-304030. Epub 2011 Feb 17. Blood. 2011. PMID: 21330472 Free PMC article.
Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb.
Grabher C, Payne EM, Johnston AB, Bolli N, Lechman E, Dick JE, Kanki JP, Look AT. Grabher C, et al. Leukemia. 2011 Mar;25(3):506-14. doi: 10.1038/leu.2010.280. Epub 2010 Nov 16. Leukemia. 2011. PMID: 21079614 Free PMC article.
Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.
Gutierrez A, Grebliunaite R, Feng H, Kozakewich E, Zhu S, Guo F, Payne E, Mansour M, Dahlberg SE, Neuberg DS, den Hertog J, Prochownik EV, Testa JR, Harris M, Kanki JP, Look AT. Gutierrez A, et al. J Exp Med. 2011 Aug 1;208(8):1595-603. doi: 10.1084/jem.20101691. Epub 2011 Jul 4. J Exp Med. 2011. PMID: 21727187 Free PMC article.
Clinical outcomes and survival of patients with myeloma and lymphoma enrolled into phase I clinical trials.
El-Sharkawi D, Ng CH, Payne EM, Yong KL, Ardeshna KM, Khwaja A, Townsend W, Popat R. El-Sharkawi D, et al. Br J Haematol. 2019 Apr;185(2):344-347. doi: 10.1111/bjh.15457. Epub 2018 Jul 5. Br J Haematol. 2019. PMID: 29978458 Clinical Trial. No abstract available.
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