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302 results
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Mucosal Vaccination with a Self-Adjuvanted Lipopeptide Is Immunogenic and Protective against Mycobacterium tuberculosis.
Ashhurst AS, McDonald DM, Hanna CC, Stanojevic VA, Britton WJ, Payne RJ. Ashhurst AS, et al. Among authors: payne rj. J Med Chem. 2019 Sep 12;62(17):8080-8089. doi: 10.1021/acs.jmedchem.9b00832. Epub 2019 Aug 16. J Med Chem. 2019. PMID: 31373811
Total Synthesis and Antimycobacterial Activity of Ohmyungsamycin A, Deoxyecumicin, and Ecumicin.
Hawkins PME, Tran W, Nagalingam G, Cheung CY, Giltrap AM, Cook GM, Britton WJ, Payne RJ. Hawkins PME, et al. Among authors: payne rj. Chemistry. 2020 Nov 26;26(66):15200-15205. doi: 10.1002/chem.202002408. Epub 2020 Oct 22. Chemistry. 2020. PMID: 32567168
Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L.
Ashhurst AS, Tang AH, Fajtová P, Yoon M, Aggarwal A, Stoye A, Larance M, Beretta L, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CK, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. Among authors: payne rj. bioRxiv. 2020 Dec 24:2020.12.23.424111. doi: 10.1101/2020.12.23.424111. Preprint. bioRxiv. 2020. PMID: 33398273 Free PMC article.
Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials.
Stoye A, Juillard A, Tang AH, Legac J, Gut J, White KL, Charman SA, Rosenthal PJ, Grau GER, Hunt NH, Payne RJ. Stoye A, et al. Among authors: payne rj. J Med Chem. 2019 Jun 13;62(11):5562-5578. doi: 10.1021/acs.jmedchem.9b00504. Epub 2019 May 22. J Med Chem. 2019. PMID: 31062592
Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice.
Hanna CC, Ashhurst AS, Quan D, Maxwell JWC, Britton WJ, Payne RJ. Hanna CC, et al. Among authors: payne rj. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2013730118. doi: 10.1073/pnas.2013730118. Proc Natl Acad Sci U S A. 2021. PMID: 33468674
Potent trivalent inhibitors of thrombin through hybridization of salivary sulfopeptides from hematophagous arthropods.
Agten S, Watson E, Ripoll-Rozada J, Dowman L, Wu M, Alwis I, Jackson S, Pereira P, Payne RJ. Agten S, et al. Among authors: payne rj. Angew Chem Int Ed Engl. 2020 Dec 20. doi: 10.1002/anie.202015127. Online ahead of print. Angew Chem Int Ed Engl. 2020. PMID: 33345438
Active surveillance for low-risk small papillary thyroid cancer in North American countries: past, present and future (bridging the gap between North American and Asian practices).
Pusztaszeri MP, Tamilia M, Payne RJ. Pusztaszeri MP, et al. Among authors: payne rj. Gland Surg. 2020 Oct;9(5):1685-1697. doi: 10.21037/gs-20-389. Gland Surg. 2020. PMID: 33224846 Free PMC article. Review.
Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates.
Calisto BM, Ripoll-Rozada J, Dowman LJ, Franck C, Agten SM, Parker BL, Veloso RC, Vale N, Gomes P, de Sanctis D, Payne RJ, Pereira PJB. Calisto BM, et al. Among authors: payne rj. Cell Chem Biol. 2020 Oct 20:S2451-9456(20)30381-0. doi: 10.1016/j.chembiol.2020.10.002. Online ahead of print. Cell Chem Biol. 2020. PMID: 33096052
Cyclic peptides can engage a single binding pocket through highly divergent modes.
Patel K, Walport LJ, Walshe JL, Solomon PD, Low JKK, Tran DH, Mouradian KS, Silva APG, Wilkinson-White L, Norman A, Franck C, Matthews JM, Guss JM, Payne RJ, Passioura T, Suga H, Mackay JP. Patel K, et al. Among authors: payne rj. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26728-26738. doi: 10.1073/pnas.2003086117. Epub 2020 Oct 12. Proc Natl Acad Sci U S A. 2020. PMID: 33046654 Free PMC article.
Are Bethesda III Thyroid Nodules More Aggressive than Bethesda IV Thyroid Nodules When Found to Be Malignant?
Turkdogan S, Pusztaszeri M, Forest VI, Hier MP, Payne RJ. Turkdogan S, et al. Among authors: payne rj. Cancers (Basel). 2020 Sep 9;12(9):2563. doi: 10.3390/cancers12092563. Cancers (Basel). 2020. PMID: 32916807 Free PMC article.
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