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Neuroprotective Effects of Cannabidiol in Hypoxic Ischemic Insult. The Therapeutic Window in Newborn Mice.
Mohammed N, Ceprian M, Jimenez L, Pazos MR, Martínez-Orgado J. Mohammed N, et al. Among authors: pazos mr. CNS Neurol Disord Drug Targets. 2017;16(1):102-108. doi: 10.2174/1871527315666160927110305. CNS Neurol Disord Drug Targets. 2017. PMID: 27686886
The cannabinoid agonist WIN55212 reduces brain damage in an in vivo model of hypoxic-ischemic encephalopathy in newborn rats.
Fernández-López D, Pazos MR, Tolón RM, Moro MA, Romero J, Lizasoain I, Martínez-Orgado J. Fernández-López D, et al. Pediatr Res. 2007 Sep;62(3):255-60. doi: 10.1203/PDR.0b013e318123fbb8. Pediatr Res. 2007. PMID: 17622949
Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.
Palazuelos J, Aguado T, Pazos MR, Julien B, Carrasco C, Resel E, Sagredo O, Benito C, Romero J, Azcoitia I, Fernández-Ruiz J, Guzmán M, Galve-Roperh I. Palazuelos J, et al. Brain. 2009 Nov;132(Pt 11):3152-64. doi: 10.1093/brain/awp239. Epub 2009 Oct 5. Brain. 2009. PMID: 19805493
Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs.
Lafuente H, Alvarez FJ, Pazos MR, Alvarez A, Rey-Santano MC, Mielgo V, Murgia-Esteve X, Hilario E, Martinez-Orgado J. Lafuente H, et al. Pediatr Res. 2011 Sep;70(3):272-7. doi: 10.1203/PDR.0b013e3182276b11. Pediatr Res. 2011. PMID: 21654550
Cannabinoids: novel medicines for the treatment of Huntington's disease.
Sagredo O, Pazos MR, Valdeolivas S, Fernandez-Ruiz J. Sagredo O, et al. Recent Pat CNS Drug Discov. 2012 Apr 1;7(1):41-8. doi: 10.2174/157488912798842278. Recent Pat CNS Drug Discov. 2012. PMID: 22280340 Review.
Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
Fernández-Ruiz J, Sagredo O, Pazos MR, García C, Pertwee R, Mechoulam R, Martínez-Orgado J. Fernández-Ruiz J, et al. Br J Clin Pharmacol. 2013 Feb;75(2):323-33. doi: 10.1111/j.1365-2125.2012.04341.x. Br J Clin Pharmacol. 2013. PMID: 22625422 Free PMC article. Review.
Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function.
Pazos MR, Cinquina V, Gómez A, Layunta R, Santos M, Fernández-Ruiz J, Martínez-Orgado J. Pazos MR, et al. Neuropharmacology. 2012 Oct;63(5):776-83. doi: 10.1016/j.neuropharm.2012.05.034. Epub 2012 May 30. Neuropharmacology. 2012. PMID: 22659086
Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: role of 5HT(1A) and CB2 receptors.
Pazos MR, Mohammed N, Lafuente H, Santos M, Martínez-Pinilla E, Moreno E, Valdizan E, Romero J, Pazos A, Franco R, Hillard CJ, Alvarez FJ, Martínez-Orgado J. Pazos MR, et al. Neuropharmacology. 2013 Aug;71:282-91. doi: 10.1016/j.neuropharm.2013.03.027. Epub 2013 Apr 12. Neuropharmacology. 2013. PMID: 23587650
Hypoxic-ischemic brain damage induces distant inflammatory lung injury in newborn piglets.
Arruza L, Pazos MR, Mohammed N, Escribano N, Lafuente H, Santos M, Alvarez-Díaz FJ, Martínez-Orgado J. Arruza L, et al. Pediatr Res. 2016 Mar;79(3):401-8. doi: 10.1038/pr.2015.87. Epub 2015 May 7. Pediatr Res. 2016. PMID: 25950454
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