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A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma.
Sivanand S, Peña-Llopis S, Zhao H, Kucejova B, Spence P, Pavia-Jimenez A, Yamasaki T, McBride DJ, Gillen J, Wolff NC, Morlock L, Lotan Y, Raj GV, Sagalowsky A, Margulis V, Cadeddu JA, Ross MT, Bentley DR, Kabbani W, Xie XJ, Kapur P, Williams NS, Brugarolas J. Sivanand S, et al. Sci Transl Med. 2012 Jun 6;4(137):137ra75. doi: 10.1126/scitranslmed.3003643. Sci Transl Med. 2012. PMID: 22674553 Free PMC article.
The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer.
Mandal R, Raab M, Rödel F, Krämer A, Kostova I, Peña-Llopis S, Häupl B, Oellerich T, Gasimli K, Sanhaji M, Becker S, Strebhardt K. Mandal R, et al. Among authors: pena llopis s. Cell Mol Life Sci. 2022 Nov 18;79(12):597. doi: 10.1007/s00018-022-04598-3. Cell Mol Life Sci. 2022. PMID: 36399280 Free PMC article.
Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma.
Kucejova B, Peña-Llopis S, Yamasaki T, Sivanand S, Tran TA, Alexander S, Wolff NC, Lotan Y, Xie XJ, Kabbani W, Kapur P, Brugarolas J. Kucejova B, et al. Mol Cancer Res. 2011 Sep;9(9):1255-65. doi: 10.1158/1541-7786.MCR-11-0302. Epub 2011 Jul 28. Mol Cancer Res. 2011. PMID: 21798997 Free PMC article.
Regulation of TFEB and V-ATPases by mTORC1.
Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J. Peña-Llopis S, et al. EMBO J. 2011 Jul 29;30(16):3242-58. doi: 10.1038/emboj.2011.257. EMBO J. 2011. PMID: 21804531 Free PMC article.
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM. Mata MA, et al. Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645. Nat Chem Biol. 2011. PMID: 21909097 Free PMC article.
BAP1 loss defines a new class of renal cell carcinoma.
Peña-Llopis S, Vega-Rubín-de-Celis S, Liao A, Leng N, Pavía-Jiménez A, Wang S, Yamasaki T, Zhrebker L, Sivanand S, Spence P, Kinch L, Hambuch T, Jain S, Lotan Y, Margulis V, Sagalowsky AI, Summerour PB, Kabbani W, Wong SW, Grishin N, Laurent M, Xie XJ, Haudenschild CD, Ross MT, Bentley DR, Kapur P, Brugarolas J. Peña-Llopis S, et al. Nat Genet. 2012 Jun 10;44(7):751-9. doi: 10.1038/ng.2323. Nat Genet. 2012. PMID: 22683710 Free PMC article.
47 results