Pearlman E - Search Results

1

Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.

Karmakar M, Katsnelson MA, Dubyak GR, Pearlman E. Karmakar M, et al. Among authors: pearlman e. Nat Commun. 2016 Feb 15;7:10555. doi: 10.1038/ncomms10555. Nat Commun. 2016. PMID: 26877061 Free PMC article.

2

TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways.

Sun Y, Karmakar M, Roy S, Ramadan RT, Williams SR, Howell S, Shive CL, Han Y, Stopford CM, Rietsch A, Pearlman E. Sun Y, et al. Among authors: pearlman e. J Immunol. 2010 Oct 1;185(7):4272-83. doi: 10.4049/jimmunol.1000874. Epub 2010 Sep 8. J Immunol. 2010. PMID: 20826748 Free PMC article.

3

ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival.

Sun Y, Karmakar M, Taylor PR, Rietsch A, Pearlman E. Sun Y, et al. Among authors: pearlman e. J Immunol. 2012 Feb 15;188(4):1884-95. doi: 10.4049/jimmunol.1102148. Epub 2012 Jan 16. J Immunol. 2012. PMID: 22250085 Free PMC article.

4

Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1.

Karmakar M, Sun Y, Hise AG, Rietsch A, Pearlman E. Karmakar M, et al. Among authors: pearlman e. J Immunol. 2012 Nov 1;189(9):4231-5. doi: 10.4049/jimmunol.1201447. Epub 2012 Sep 28. J Immunol. 2012. PMID: 23024281 Free PMC article.

5

Innate immune regulation of Serratia marcescens-induced corneal inflammation and infection.

Zhou R, Zhang R, Sun Y, Platt S, Szczotka-Flynn L, Pearlman E. Zhou R, et al. Among authors: pearlman e. Invest Ophthalmol Vis Sci. 2012 Oct 25;53(11):7382-8. doi: 10.1167/iovs.12-10238. Invest Ophthalmol Vis Sci. 2012. PMID: 23033384 Free PMC article.

6

Host defense at the ocular surface.

Pearlman E, Sun Y, Roy S, Karmakar M, Hise AG, Szczotka-Flynn L, Ghannoum M, Chinnery HR, McMenamin PG, Rietsch A. Pearlman E, et al. Int Rev Immunol. 2013 Feb;32(1):4-18. doi: 10.3109/08830185.2012.749400. Int Rev Immunol. 2013. PMID: 23360155 Free PMC article. Review.

7

CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo.

Roy S, Karmakar M, Pearlman E. Roy S, et al. Among authors: pearlman e. J Biol Chem. 2014 Jan 10;289(2):1174-82. doi: 10.1074/jbc.M113.523167. Epub 2013 Nov 25. J Biol Chem. 2014. PMID: 24275652 Free PMC article.

8

Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2.

Taylor PR, Roy S, Leal SM Jr, Sun Y, Howell SJ, Cobb BA, Li X, Pearlman E. Taylor PR, et al. Among authors: pearlman e. Nat Immunol. 2014 Feb;15(2):143-51. doi: 10.1038/ni.2797. Epub 2013 Dec 22. Nat Immunol. 2014. PMID: 24362892 Free PMC article.

9

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E. Karmakar M, et al. Among authors: pearlman e. J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624. Epub 2015 Jan 21. J Immunol. 2015. PMID: 25609842 Free PMC article.

10

Inhibition of Corneal Inflammation by the Resolvin E1.

Lee JE, Sun Y, Gjorstrup P, Pearlman E. Lee JE, et al. Among authors: pearlman e. Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2728-36. doi: 10.1167/iovs.14-15982. Invest Ophthalmol Vis Sci. 2015. PMID: 25758817 Free PMC article.

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