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Novel hopanoid cyclases from the environment.
Pearson A, Flood Page SR, Jorgenson TL, Fischer WW, Higgins MB. Pearson A, et al. Environ Microbiol. 2007 Sep;9(9):2175-88. doi: 10.1111/j.1462-2920.2007.01331.x. Environ Microbiol. 2007. PMID: 17686016
A better understanding of the contemporary distribution of hopanoid biosynthesis may reveal fundamental insight about the function of these compounds, the organisms in which they are found, and the environmental signals preserved in the sedimentary record....
A better understanding of the contemporary distribution of hopanoid biosynthesis may reveal fundamental insight about the function of
Phylogenetic and biochemical evidence for sterol synthesis in the bacterium Gemmata obscuriglobus.
Pearson A, Budin M, Brocks JJ. Pearson A, et al. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15352-7. doi: 10.1073/pnas.2536559100. Epub 2003 Dec 5. Proc Natl Acad Sci U S A. 2003. PMID: 14660793 Free PMC article.
Sterol biosynthesis is viewed primarily as a eukaryotic process, and the frequency of its occurrence in bacteria has long been a subject of controversy. ...In bacteria, the sterol biosynthesis genes occupy a contiguous coding region and possibly comprise a
Sterol biosynthesis is viewed primarily as a eukaryotic process, and the frequency of its occurrence in bacteria has long been a
Nonmarine crenarchaeol in Nevada hot springs.
Pearson A, Huang Z, Ingalls AE, Romanek CS, Wiegel J, Freeman KH, Smittenberg RH, Zhang CL. Pearson A, et al. Appl Environ Microbiol. 2004 Sep;70(9):5229-37. doi: 10.1128/AEM.70.9.5229-5237.2004. Appl Environ Microbiol. 2004. PMID: 15345404 Free PMC article.
The structurally unusual GDGT crenarchaeol has been proposed as a taxonomically specific biomarker for the marine planktonic group I archaea. ...Instead, a significant correlation with the concentration of bicarbonate was observed. Archaeal DNA was analyzed by denat …
The structurally unusual GDGT crenarchaeol has been proposed as a taxonomically specific biomarker for the marine planktonic group I …
Quantifying archaeal community autotrophy in the mesopelagic ocean using natural radiocarbon.
Ingalls AE, Shah SR, Hansman RL, Aluwihare LI, Santos GM, Druffel ER, Pearson A. Ingalls AE, et al. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6442-7. doi: 10.1073/pnas.0510157103. Epub 2006 Apr 13. Proc Natl Acad Sci U S A. 2006. PMID: 16614070 Free PMC article.
If archaea live primarily as autotrophs in the natural environment, a large ammonia-oxidizing population would play a significant role in marine nitrification. ...The data suggest either that the marine archaeal community includes both autotrophs and heterotrophs or …
If archaea live primarily as autotrophs in the natural environment, a large ammonia-oxidizing population would play a signific …
Thermophilic temperature optimum for crenarchaeol synthesis and its implication for archaeal evolution.
Zhang CL, Pearson A, Li YL, Mills G, Wiegel J. Zhang CL, et al. Appl Environ Microbiol. 2006 Jun;72(6):4419-22. doi: 10.1128/AEM.00191-06. Appl Environ Microbiol. 2006. PMID: 16751559 Free PMC article.
Terrestrial and marine data together suggest a maximum relative abundance of crenarchaeol at approximately 40 degrees C. This warm temperature optimum may have facilitated colonization of the ocean by (hyper)thermophilic Archaea and the major marine radiation of Crenarchae …
Terrestrial and marine data together suggest a maximum relative abundance of crenarchaeol at approximately 40 degrees C. This warm te …
Isolation, characterization, and ecology of sulfur-respiring crenarchaea inhabiting acid-sulfate-chloride-containing geothermal springs in Yellowstone National Park.
Boyd ES, Jackson RA, Encarnacion G, Zahn JA, Beard T, Leavitt WD, Pi Y, Zhang CL, Pearson A, Geesey GG. Boyd ES, et al. Appl Environ Microbiol. 2007 Oct;73(20):6669-77. doi: 10.1128/AEM.01321-07. Epub 2007 Aug 24. Appl Environ Microbiol. 2007. PMID: 17720836 Free PMC article.
Physiological characterization suggests that the isolates are adapted to the physicochemical conditions of Dragon Spring and can utilize the natural organic matter in the spring as a carbon and energy source. ...
Physiological characterization suggests that the isolates are adapted to the physicochemical conditions of Dragon Spring and can utilize the …
Quantifying microbial utilization of petroleum hydrocarbons in salt marsh sediments by using the 13C content of bacterial rRNA.
Pearson A, Kraunz KS, Sessions AL, Dekas AE, Leavitt WD, Edwards KJ. Pearson A, et al. Appl Environ Microbiol. 2008 Feb;74(4):1157-66. doi: 10.1128/AEM.01014-07. Epub 2007 Dec 14. Appl Environ Microbiol. 2008. PMID: 18083852 Free PMC article.
Here we took a whole-community approach to investigate bacterial incorporation of petroleum hydrocarbons from a simulated oil spill. ...Magnetic bead capture methods for selective recovery of bacterial RNA were used to monitor the 13C content of bacterial biomass du …
Here we took a whole-community approach to investigate bacterial incorporation of petroleum hydrocarbons from a simulated oil …
Factors controlling the distribution of archaeal tetraethers in terrestrial hot springs.
Pearson A, Pi Y, Zhao W, Li W, Li Y, Inskeep W, Perevalova A, Romanek C, Li S, Zhang CL. Pearson A, et al. Appl Environ Microbiol. 2008 Jun;74(11):3523-32. doi: 10.1128/AEM.02450-07. Epub 2008 Apr 4. Appl Environ Microbiol. 2008. PMID: 18390673 Free PMC article.
Here, we examined profiles of GDGTs from pure cultures of Crenarchaeota and from terrestrial geothermal springs representing a wide distribution of locations, including Yellowstone National Park (United States), the Great Basin of Nevada and California (United States), Kam …
Here, we examined profiles of GDGTs from pure cultures of Crenarchaeota and from terrestrial geothermal springs representing a wide d …
A polycyclic terpenoid that alleviates oxidative stress.
Bosak T, Losick RM, Pearson A. Bosak T, et al. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6725-9. doi: 10.1073/pnas.0800199105. Epub 2008 Apr 24. Proc Natl Acad Sci U S A. 2008. PMID: 18436644 Free PMC article.
A persistent question remains: Did some polycyclic lipids initially evolve in response to certain environmental or metabolic stresses, including the presence of oxygen? ...We show that these molecules increase the resistance of spores to a reactive oxygen species, d
A persistent question remains: Did some polycyclic lipids initially evolve in response to certain environmental or metabolic stresses
Sterols in red and green algae: quantification, phylogeny, and relevance for the interpretation of geologic steranes.
Kodner RB, Pearson A, Summons RE, Knoll AH. Kodner RB, et al. Geobiology. 2008 Aug;6(4):411-20. doi: 10.1111/j.1472-4669.2008.00167.x. Epub 2008 Jul 9. Geobiology. 2008. PMID: 18624688
Steroids, a class of triterpenoid lipids with high preservation potential, are widely distributed in sedimentary rocks. All eukaryotes have a physiological requirement for these molecules, making steroids important biomarkers for aiding our understanding of eukaryot …
Steroids, a class of triterpenoid lipids with high preservation potential, are widely distributed in sedimentary rocks. All eukaryote …
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