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148 results
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Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1alpha gene mutations: evidence for pharmacogenetics in diabetes.
Pearson ER, Liddell WG, Shepherd M, Corrall RJ, Hattersley AT. Pearson ER, et al. Diabet Med. 2000 Jul;17(7):543-5. doi: 10.1046/j.1464-5491.2000.00305.x. Diabet Med. 2000. PMID: 10972586
Unravelling the heterogeneity of non insulin dependent diabetes.
Pearson ER, Hattersley AT. Pearson ER, et al. J R Coll Physicians Lond. 2000 Jul-Aug;34(4):332-5. J R Coll Physicians Lond. 2000. PMID: 11005066 Review. No abstract available.
beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations.
Pearson ER, Velho G, Clark P, Stride A, Shepherd M, Frayling TM, Bulman MP, Ellard S, Froguel P, Hattersley AT. Pearson ER, et al. Diabetes. 2001 Feb;50 Suppl 1:S101-7. doi: 10.2337/diabetes.50.2007.s101. Diabetes. 2001. PMID: 11272165
beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.
Frayling TM, Evans JC, Bulman MP, Pearson E, Allen L, Owen K, Bingham C, Hannemann M, Shepherd M, Ellard S, Hattersley AT. Frayling TM, et al. Diabetes. 2001 Feb;50 Suppl 1:S94-100. doi: 10.2337/diabetes.50.2007.s94. Diabetes. 2001. PMID: 11272211
Severe hyperglycemia after renal transplantation in a pediatric patient with a mutation of the hepatocyte nuclear factor-1beta gene.
Waller SC, Rees L, Woolf AS, Ellard S, Pearson ER, Hattersley AT, Bingham C. Waller SC, et al. Among authors: pearson er. Am J Kidney Dis. 2002 Dec;40(6):1325-30. doi: 10.1053/ajkd.2002.36915. Am J Kidney Dis. 2002. PMID: 12460054
Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation.
Bingham C, Ellard S, van't Hoff WG, Simmonds HA, Marinaki AM, Badman MK, Winocour PH, Stride A, Lockwood CR, Nicholls AJ, Owen KR, Spyer G, Pearson ER, Hattersley AT. Bingham C, et al. Among authors: pearson er. Kidney Int. 2003 May;63(5):1645-51. doi: 10.1046/j.1523-1755.2003.00903.x. Kidney Int. 2003. PMID: 12675839
Genetic cause of hyperglycaemia and response to treatment in diabetes.
Pearson ER, Starkey BJ, Powell RJ, Gribble FM, Clark PM, Hattersley AT. Pearson ER, et al. Lancet. 2003 Oct 18;362(9392):1275-81. doi: 10.1016/S0140-6736(03)14571-0. Lancet. 2003. PMID: 14575972 Clinical Trial.
No deterioration in glycemic control in HNF-1alpha maturity-onset diabetes of the young following transfer from long-term insulin to sulphonylureas.
Shepherd M, Pearson ER, Houghton J, Salt G, Ellard S, Hattersley AT. Shepherd M, et al. Among authors: pearson er. Diabetes Care. 2003 Nov;26(11):3191-2. doi: 10.2337/diacare.26.11.3191-a. Diabetes Care. 2003. PMID: 14578267 Clinical Trial. No abstract available.
Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.
Richter S, Shih DQ, Pearson ER, Wolfrum C, Fajans SS, Hattersley AT, Stoffel M. Richter S, et al. Among authors: pearson er. Diabetes. 2003 Dec;52(12):2989-95. doi: 10.2337/diabetes.52.12.2989. Diabetes. 2003. PMID: 14633861
Contrasting diabetes phenotypes associated with hepatocyte nuclear factor-1alpha and -1beta mutations.
Pearson ER, Badman MK, Lockwood CR, Clark PM, Ellard S, Bingham C, Hattersley AT. Pearson ER, et al. Diabetes Care. 2004 May;27(5):1102-7. doi: 10.2337/diacare.27.5.1102. Diabetes Care. 2004. PMID: 15111528
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