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Regulation of p70s6k/p85s6k and its role in the cell cycle.
Pearson RB, Thomas G. Pearson RB, et al. Prog Cell Cycle Res. 1995;1:21-32. doi: 10.1007/978-1-4615-1809-9_3. Prog Cell Cycle Res. 1995. PMID: 9552351 Review.
Dual requirement for a newly identified phosphorylation site in p70s6k.
Moser BA, Dennis PB, Pullen N, Pearson RB, Williamson NA, Wettenhall RE, Kozma SC, Thomas G. Moser BA, et al. Mol Cell Biol. 1997 Sep;17(9):5648-55. doi: 10.1128/mcb.17.9.5648. Mol Cell Biol. 1997. PMID: 9271440 Free PMC article.
Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.
Jefferies HB, Fumagalli S, Dennis PB, Reinhard C, Pearson RB, Thomas G. Jefferies HB, et al. EMBO J. 1997 Jun 16;16(12):3693-704. doi: 10.1093/emboj/16.12.3693. EMBO J. 1997. PMID: 9218810 Free PMC article.
Phosphorylation of nuclear phospholipase C beta1 by extracellular signal-regulated kinase mediates the mitogenic action of insulin-like growth factor I.
Xu A, Suh PG, Marmy-Conus N, Pearson RB, Seok OY, Cocco L, Gilmour RS. Xu A, et al. Mol Cell Biol. 2001 May;21(9):2981-90. doi: 10.1128/MCB.21.9.2981-2990.2001. Mol Cell Biol. 2001. PMID: 11287604 Free PMC article.
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
Kusnadi EP, Trigos AS, Cullinane C, Goode DL, Larsson O, Devlin JR, Chan KT, De Souza DP, McConville MJ, McArthur GA, Thomas G, Sanij E, Poortinga G, Hannan RD, Hannan KM, Kang J, Pearson RB. Kusnadi EP, et al. Among authors: pearson rb. EMBO J. 2020 Sep 18:e105111. doi: 10.15252/embj.2020105111. Online ahead of print. EMBO J. 2020. PMID: 32945574
rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461.
Son J, Hannan KM, Poortinga G, Hein N, Cameron DP, Ganley ARD, Sheppard KE, Pearson RB, Hannan RD, Sanij E. Son J, et al. Among authors: pearson rb. Front Cell Dev Biol. 2020 Jul 3;8:568. doi: 10.3389/fcell.2020.00568. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32719798 Free PMC article.
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.
Gao J, Jung M, Mayoh C, Venkat P, Hannan KM, Fletcher JI, Kamili A, Gifford AJ, Kusnadi EP, Pearson RB, Hannan RD, Haber M, Norris MD, Somers K, Henderson MJ. Gao J, et al. Among authors: pearson rb. Cancer Res. 2020 Sep 1;80(17):3706-3718. doi: 10.1158/0008-5472.CAN-19-3914. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651259
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