Pearson RM - Search Results

1

Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease.

Freitag TL, Podojil JR, Pearson RM, Fokta FJ, Sahl C, Messing M, Andersson LC, Leskinen K, Saavalainen P, Hoover LI, Huang K, Phippard D, Maleki S, King NJC, Shea LD, Miller SD, Meri SK, Getts DR. Freitag TL, et al. Among authors: pearson rm. Gastroenterology. 2020 May;158(6):1667-1681.e12. doi: 10.1053/j.gastro.2020.01.045. Epub 2020 Feb 4. Gastroenterology. 2020. PMID: 32032584 Free PMC article.

2

Biodegradable antigen-associated PLG nanoparticles tolerize Th2-mediated allergic airway inflammation pre- and postsensitization.

Smarr CB, Yap WT, Neef TP, Pearson RM, Hunter ZN, Ifergan I, Getts DR, Bryce PJ, Shea LD, Miller SD. Smarr CB, et al. Among authors: pearson rm. Proc Natl Acad Sci U S A. 2016 May 3;113(18):5059-64. doi: 10.1073/pnas.1505782113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091976 Free PMC article.

3

An antigen-encapsulating nanoparticle platform for T_H1/17 immune tolerance therapy.

McCarthy DP, Yap JW, Harp CT, Song WK, Chen J, Pearson RM, Miller SD, Shea LD. McCarthy DP, et al. Among authors: pearson rm. Nanomedicine. 2017 Jan;13(1):191-200. doi: 10.1016/j.nano.2016.09.007. Epub 2016 Oct 6. Nanomedicine. 2017. PMID: 27720992 Free PMC article.

4

In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.

Pearson RM, Casey LM, Hughes KR, Miller SD, Shea LD. Pearson RM, et al. Adv Drug Deliv Rev. 2017 May 15;114:240-255. doi: 10.1016/j.addr.2017.04.005. Epub 2017 Apr 14. Adv Drug Deliv Rev. 2017. PMID: 28414079 Free PMC article. Review.

5

Controlled Delivery of Single or Multiple Antigens in Tolerogenic Nanoparticles Using Peptide-Polymer Bioconjugates.

Pearson RM, Casey LM, Hughes KR, Wang LZ, North MG, Getts DR, Miller SD, Shea LD. Pearson RM, et al. Mol Ther. 2017 Jul 5;25(7):1655-1664. doi: 10.1016/j.ymthe.2017.04.015. Epub 2017 May 5. Mol Ther. 2017. PMID: 28479234 Free PMC article.

6

Conjugation of Transforming Growth Factor Beta to Antigen-Loaded Poly(lactide- co-glycolide) Nanoparticles Enhances Efficiency of Antigen-Specific Tolerance.

Casey LM, Pearson RM, Hughes KR, Liu JMH, Rose JA, North MG, Wang LZ, Lei M, Miller SD, Shea LD. Casey LM, et al. Among authors: pearson rm. Bioconjug Chem. 2018 Mar 21;29(3):813-823. doi: 10.1021/acs.bioconjchem.7b00624. Epub 2017 Nov 30. Bioconjug Chem. 2018. PMID: 29148731 Free PMC article.

7

Overcoming challenges in treating autoimmuntity: Development of tolerogenic immune-modifying nanoparticles.

Pearson RM, Podojil JR, Shea LD, King NJC, Miller SD, Getts DR. Pearson RM, et al. Nanomedicine. 2019 Jun;18:282-291. doi: 10.1016/j.nano.2018.10.001. Epub 2018 Oct 21. Nanomedicine. 2019. PMID: 30352312 Free PMC article. Review.

8

Localized immune tolerance from FasL-functionalized PLG scaffolds.

Skoumal M, Woodward KB, Zhao H, Wang F, Yolcu ES, Pearson RM, Hughes KR, García AJ, Shea LD, Shirwan H. Skoumal M, et al. Among authors: pearson rm. Biomaterials. 2019 Feb;192:271-281. doi: 10.1016/j.biomaterials.2018.11.015. Epub 2018 Nov 13. Biomaterials. 2019. PMID: 30458362 Free PMC article.

9

Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation.

Saito E, Kuo R, Pearson RM, Gohel N, Cheung B, King NJC, Miller SD, Shea LD. Saito E, et al. Among authors: pearson rm. J Control Release. 2019 Apr 28;300:185-196. doi: 10.1016/j.jconrel.2019.02.025. Epub 2019 Feb 27. J Control Release. 2019. PMID: 30822435 Free PMC article.

10

Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation.

Casey LM, Kakade S, Decker JT, Rose JA, Deans K, Shea LD, Pearson RM. Casey LM, et al. Among authors: pearson rm. Biomaterials. 2019 Oct;218:119333. doi: 10.1016/j.biomaterials.2019.119333. Epub 2019 Jul 4. Biomaterials. 2019. PMID: 31301576 Free PMC article.

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