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Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. King MA, et al. Among authors: pearson t. Clin Exp Immunol. 2009 Jul;157(1):104-18. doi: 10.1111/j.1365-2249.2009.03933.x. Clin Exp Immunol. 2009. PMID: 19659776 Free PMC article.
Humanized SCID mouse models for biomedical research.
Pearson T, Greiner DL, Shultz LD. Pearson T, et al. Curr Top Microbiol Immunol. 2008;324:25-51. doi: 10.1007/978-3-540-75647-7_2. Curr Top Microbiol Immunol. 2008. PMID: 18481451 Review.
Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.
Pearson T, Shultz LD, Miller D, King M, Laning J, Fodor W, Cuthbert A, Burzenski L, Gott B, Lyons B, Foreman O, Rossini AA, Greiner DL. Pearson T, et al. Clin Exp Immunol. 2008 Nov;154(2):270-84. doi: 10.1111/j.1365-2249.2008.03753.x. Epub 2008 Sep 8. Clin Exp Immunol. 2008. PMID: 18785974 Free PMC article.
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL. King M, et al. Among authors: pearson t. Clin Immunol. 2008 Mar;126(3):303-14. doi: 10.1016/j.clim.2007.11.001. Epub 2007 Dec 21. Clin Immunol. 2008. PMID: 18096436
Creation of "humanized" mice to study human immunity.
Pearson T, Greiner DL, Shultz LD. Pearson T, et al. Curr Protoc Immunol. 2008 May;Chapter 15:15.21.1-15.21.21. doi: 10.1002/0471142735.im1521s81. Curr Protoc Immunol. 2008. PMID: 18491294 Free PMC article.
1,326 results