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Breaking tolerance with engineered class I antigen-presenting molecules.
Parks CA, Henning KR, Pavelko KD, Hansen MJ, Van Keulen VP, Reed BK, Stone JD, Schrum AG, Gil D, Kranz DM, Bordner AJ, Barry MA, Pease LR. Parks CA, et al. Among authors: pease lr. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3136-3145. doi: 10.1073/pnas.1807465116. Epub 2019 Feb 6. Proc Natl Acad Sci U S A. 2019. PMID: 30728302 Free PMC article.
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts.
Sterner RM, Sakemura R, Cox MJ, Yang N, Khadka RH, Forsman CL, Hansen MJ, Jin F, Ayasoufi K, Hefazi M, Schick KJ, Walters DK, Ahmed O, Chappell D, Sahmoud T, Durrant C, Nevala WK, Patnaik MM, Pease LR, Hedin KE, Kay NE, Johnson AJ, Kenderian SS. Sterner RM, et al. Among authors: pease lr. Blood. 2019 Feb 14;133(7):697-709. doi: 10.1182/blood-2018-10-881722. Epub 2018 Nov 21. Blood. 2019. PMID: 30463995 Free PMC article.
The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network.
Neier SC, Ferrer A, Wilton KM, Smith SEP, Kelcher AMH, Pavelko KD, Canfield JM, Davis TR, Stiles RJ, Chen Z, McCluskey J, Burrows SR, Rossjohn J, Hebrink DM, Carmona EM, Limper AH, Kappes DJ, Wettstein PJ, Johnson AJ, Pease LR, Daniels MA, Neuhauser C, Gil D, Schrum AG. Neier SC, et al. Among authors: pease lr. Sci Immunol. 2019 Feb 15;4(32):eaal2201. doi: 10.1126/sciimmunol.aal2201. Sci Immunol. 2019. PMID: 30770409 Free PMC article.
212 results