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Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.
Ansari MA, Pedergnana V, L C Ip C, Magri A, Von Delft A, Bonsall D, Chaturvedi N, Bartha I, Smith D, Nicholson G, McVean G, Trebes A, Piazza P, Fellay J, Cooke G, Foster GR; STOP-HCV Consortium; Hudson E, McLauchlan J, Simmonds P, Bowden R, Klenerman P, Barnes E, Spencer CCA. Ansari MA, et al. Among authors: pedergnana v. Nat Genet. 2017 May;49(5):666-673. doi: 10.1038/ng.3835. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394351 Free PMC article.
Interferon lambda 4 impacts the genetic diversity of hepatitis C virus.
Ansari MA, Aranday-Cortes E, Ip CL, da Silva Filipe A, Lau SH, Bamford C, Bonsall D, Trebes A, Piazza P, Sreenu V, Cowton VM; STOP-HCV Consortium; Hudson E, Bowden R, Patel AH, Foster GR, Irving WL, Agarwal K, Thomson EC, Simmonds P, Klenerman P, Holmes C, Barnes E, Spencer CC, McLauchlan J, Pedergnana V. Ansari MA, et al. Among authors: pedergnana v. Elife. 2019 Sep 3;8:e42463. doi: 10.7554/eLife.42463. Elife. 2019. PMID: 31478835 Free PMC article.
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure.
Smith DA, Fernandez-Antunez C, Magri A, Bowden R, Chaturvedi N, Fellay J, McLauchlan J, Foster GR, Irving WL; STOP-HCV Consortium; Simmonds P, Pedergnana V, Ramirez S, Bukh J, Barnes E, Ansari MA. Smith DA, et al. Among authors: pedergnana v. Nat Commun. 2021 Oct 20;12(1):6105. doi: 10.1038/s41467-021-25649-6. Nat Commun. 2021. PMID: 34671027 Free PMC article.
Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome.
Lucas M, Deshpande P, James I, Rauch A, Pfafferott K, Gaylard E, Merani S, Plauzolles A, Lucas A, McDonnell W, Kalams S, Pilkinton M, Chastain C, Barnett L, Prosser A, Mallal S, Fitzmaurice K, Drummer H, Ansari MA, Pedergnana V, Barnes E, John M, Kelleher D, Klenerman P, Gaudieri S. Lucas M, et al. Among authors: pedergnana v. Sci Rep. 2018 May 8;8(1):7224. doi: 10.1038/s41598-018-25559-6. Sci Rep. 2018. PMID: 29740042 Free PMC article.
Comprehensive Comparative Analysis of Standard Validated, Genetic, and Novel Biomarkers to Enhance Prognostic Risk-Stratification in Patients With Hepatitis C Virus Cirrhosis.
Innes H, Walker AJ, Benselin J, Grove JI, Pedergnana V, Azim Ansari M, Lin SK, McLauchlan J, Hutchinson SJ, Barnes E, Irving WL, Guha IN; on behalf of the HCV Research UK; & STOP-HCV; Consortia. Innes H, et al. Among authors: pedergnana v. Clin Transl Gastroenterol. 2022 Feb 9;13(3):e00462. doi: 10.14309/ctg.0000000000000462. Clin Transl Gastroenterol. 2022. PMID: 35142723 Free PMC article.
38 results