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Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase.
Ko YH, Pedersen PL, Geschwind JF. Ko YH, et al. Among authors: pedersen pl. Cancer Lett. 2001 Nov 8;173(1):83-91. doi: 10.1016/s0304-3835(01)00667-x. Cancer Lett. 2001. PMID: 11578813
The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside.
Azevedo-Silva J, Queirós O, Baltazar F, Ułaszewski S, Goffeau A, Ko YH, Pedersen PL, Preto A, Casal M. Azevedo-Silva J, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 2016 Aug;48(4):349-62. doi: 10.1007/s10863-016-9670-z. Epub 2016 Jul 25. J Bioenerg Biomembr. 2016. PMID: 27457582 Review.
The oligomycin sensitivity conferring protein of rat liver mitochondrial ATP synthase: arginine 94 is important for the binding of OSCP to F1.
Golden TR, Pedersen PL. Golden TR, et al. Among authors: pedersen pl. Biochemistry. 1998 Sep 29;37(39):13871-81. doi: 10.1021/bi981120a. Biochemistry. 1998. PMID: 9753477
Delta subunit of rat liver mitochondrial ATP synthase: molecular description and novel insights into the nature of its association with the F1-moiety.
Pan W, Ko YH, Pedersen PL. Pan W, et al. Among authors: pedersen pl. Biochemistry. 1998 May 12;37(19):6911-23. doi: 10.1021/bi9800698. Biochemistry. 1998. PMID: 9578578
Although recently shown to associate tightly with the beta subunit [Pedersen, P. L., Hullihen, J., Bianchet, M., Amzel, L. M., and Lebowitz, M. ...
Although recently shown to associate tightly with the beta subunit [Pedersen, P. L., Hullihen, J., Bianchet, M., Amzel, L. M., and Le …
Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase.
Mathupala SP, Rempel A, Pedersen PL. Mathupala SP, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 1997 Aug;29(4):339-43. doi: 10.1023/a:1022494613613. J Bioenerg Biomembr. 1997. PMID: 9387094 Review.
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53.
Mathupala SP, Heese C, Pedersen PL. Mathupala SP, et al. Among authors: pedersen pl. J Biol Chem. 1997 Sep 5;272(36):22776-80. doi: 10.1074/jbc.272.36.22776. J Biol Chem. 1997. PMID: 9278438
., and Pedersen, P. L. (1995) J. Biol. Chem. 270, 16918-16925). Here, we show that a p53 protein, exhibiting two point mutations in its cDNA, is abundantly expressed in the AS-30D hepatoma. ...
., and Pedersen, P. L. (1995) J. Biol. Chem. 270, 16918-16925). Here, we show that a p53 protein, exhibiting two point mutations in i …
Protein inhibitor of mitochondrial ATP synthase: relationship of inhibitor structure to pH-dependent regulation.
Lebowitz MS, Pedersen PL. Lebowitz MS, et al. Among authors: pedersen pl. Arch Biochem Biophys. 1996 Jun 15;330(2):342-54. doi: 10.1006/abbi.1996.0261. Arch Biochem Biophys. 1996. PMID: 8660664
Glucose catabolism in African trypanosomes. Evidence that the terminal step is catalyzed by a pyruvate transporter capable of facilitating uptake of toxic analogs.
Barnard JP, Reynafarje B, Pedersen PL. Barnard JP, et al. Among authors: pedersen pl. J Biol Chem. 1993 Feb 15;268(5):3654-61. J Biol Chem. 1993. PMID: 8429041
Structure/function relationships in hexokinase. Site-directed mutational analyses and characterization of overexpressed fragments implicate different functions for the N- and C-terminal halves of the enzyme.
Arora KK, Filburn CR, Pedersen PL. Arora KK, et al. Among authors: pedersen pl. J Biol Chem. 1993 Aug 25;268(24):18259-66. J Biol Chem. 1993. PMID: 8349702
., and Pedersen, P. L. (1991) J. Biol. Chem. 266, 5359-5362). Here we have assessed also the role of the N-terminal half of the same enzyme. ...
., and Pedersen, P. L. (1991) J. Biol. Chem. 266, 5359-5362). Here we have assessed also the role of the N-terminal half of the same …
Glucose utilization by tumor cells: the enzyme hexokinase autophosphorylates both its N- and C-terminal halves.
Arora KK, Pedersen PL. Arora KK, et al. Among authors: pedersen pl. Arch Biochem Biophys. 1993 Aug 1;304(2):515-8. doi: 10.1006/abbi.1993.1384. Arch Biochem Biophys. 1993. PMID: 8346927 No abstract available.
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