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The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide.
Thomas PJ, Shenbagamurthi P, Sondek J, Hullihen JM, Pedersen PL. Thomas PJ, et al. Among authors: pedersen pl. J Biol Chem. 1992 Mar 25;267(9):5727-30. J Biol Chem. 1992. PMID: 1372891
., and Pedersen, P. L. (1991) Science 251, 555-557). A peptide lacking this critical residue, but otherwise corresponding to this crucial part of the protein, now also has been chemically synthesized and purified. ...
., and Pedersen, P. L. (1991) Science 251, 555-557). A peptide lacking this critical residue, but otherwise corresponding to this cru …
Notes on the mechanism of ATP synthesis.
Bianchet MA, Pedersen PL, Amzel LM. Bianchet MA, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 2000 Oct;32(5):517-21. doi: 10.1023/a:1005673209883. J Bioenerg Biomembr. 2000. PMID: 15254387
ATP synthases in the year 2000: defining the different levels of mechanism and getting a grip on each.
Pedersen PL, Ko YH, Hong S. Pedersen PL, et al. J Bioenerg Biomembr. 2000 Oct;32(5):423-32. doi: 10.1023/a:1005652605340. J Bioenerg Biomembr. 2000. PMID: 15254377 Review.
Cystic fibrosis: a brief look at some highlights of a decade of research focused on elucidating and correcting the molecular basis of the disease.
Ko YH, Pedersen PL. Ko YH, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 2001 Dec;33(6):513-21. doi: 10.1023/a:1012831322753. J Bioenerg Biomembr. 2001. PMID: 11804193 Review.
Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR).
Bianchet MA, Ko YH, Amzel LM, Pedersen PL. Bianchet MA, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 1997 Oct;29(5):503-24. doi: 10.1023/a:1022443209010. J Bioenerg Biomembr. 1997. PMID: 9511935
., and Pedersen, P.L. (1995) J. Biol. Chem. 268, 24330-24338], providing support for the model. In contrast, the second nucleotide binding fold is predicted at best to be a weak ATPase as the glutamic acid residue is replaced with a glutamine. ...
., and Pedersen, P.L. (1995) J. Biol. Chem. 268, 24330-24338], providing support for the model. In contrast, the second nucleotide bi …
Frontiers in ATP synthase research: understanding the relationship between subunit movements and ATP synthesis.
Pedersen PL. Pedersen PL. J Bioenerg Biomembr. 1996 Oct;28(5):389-95. doi: 10.1007/BF02113979. J Bioenerg Biomembr. 1996. PMID: 8951084 Review.
Frontiers in research on cystic fibrosis: understanding its molecular and chemical basis and relationship to the pathogenesis of the disease.
Ko YH, Pedersen PL. Ko YH, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 1997 Oct;29(5):417-27. doi: 10.1023/a:1022402105375. J Bioenerg Biomembr. 1997. PMID: 9511927 Review.
The oligomycin sensitivity conferring protein of rat liver mitochondrial ATP synthase: arginine 94 is important for the binding of OSCP to F1.
Golden TR, Pedersen PL. Golden TR, et al. Among authors: pedersen pl. Biochemistry. 1998 Sep 29;37(39):13871-81. doi: 10.1021/bi981120a. Biochemistry. 1998. PMID: 9753477
Delta subunit of rat liver mitochondrial ATP synthase: molecular description and novel insights into the nature of its association with the F1-moiety.
Pan W, Ko YH, Pedersen PL. Pan W, et al. Among authors: pedersen pl. Biochemistry. 1998 May 12;37(19):6911-23. doi: 10.1021/bi9800698. Biochemistry. 1998. PMID: 9578578
Although recently shown to associate tightly with the beta subunit [Pedersen, P. L., Hullihen, J., Bianchet, M., Amzel, L. M., and Lebowitz, M. ...
Although recently shown to associate tightly with the beta subunit [Pedersen, P. L., Hullihen, J., Bianchet, M., Amzel, L. M., and Le …
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53.
Mathupala SP, Heese C, Pedersen PL. Mathupala SP, et al. Among authors: pedersen pl. J Biol Chem. 1997 Sep 5;272(36):22776-80. doi: 10.1074/jbc.272.36.22776. J Biol Chem. 1997. PMID: 9278438
., and Pedersen, P. L. (1995) J. Biol. Chem. 270, 16918-16925). Here, we show that a p53 protein, exhibiting two point mutations in its cDNA, is abundantly expressed in the AS-30D hepatoma. ...
., and Pedersen, P. L. (1995) J. Biol. Chem. 270, 16918-16925). Here, we show that a p53 protein, exhibiting two point mutations in i …
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