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Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53.
Mathupala SP, Heese C, Pedersen PL. Mathupala SP, et al. Among authors: pedersen pl. J Biol Chem. 1997 Sep 5;272(36):22776-80. doi: 10.1074/jbc.272.36.22776. J Biol Chem. 1997. PMID: 9278438
., and Pedersen, P. L. (1995) J. Biol. Chem. 270, 16918-16925). Here, we show that a p53 protein, exhibiting two point mutations in its cDNA, is abundantly expressed in the AS-30D hepatoma. ...
., and Pedersen, P. L. (1995) J. Biol. Chem. 270, 16918-16925). Here, we show that a p53 protein, exhibiting two point mutations in i …
Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR).
Bianchet MA, Ko YH, Amzel LM, Pedersen PL. Bianchet MA, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 1997 Oct;29(5):503-24. doi: 10.1023/a:1022443209010. J Bioenerg Biomembr. 1997. PMID: 9511935
., and Pedersen, P.L. (1995) J. Biol. Chem. 268, 24330-24338], providing support for the model. In contrast, the second nucleotide binding fold is predicted at best to be a weak ATPase as the glutamic acid residue is replaced with a glutamine. ...
., and Pedersen, P.L. (1995) J. Biol. Chem. 268, 24330-24338], providing support for the model. In contrast, the second nucleotide bi …
Frontiers in ATP synthase research: understanding the relationship between subunit movements and ATP synthesis.
Pedersen PL. Pedersen PL. J Bioenerg Biomembr. 1996 Oct;28(5):389-95. doi: 10.1007/BF02113979. J Bioenerg Biomembr. 1996. PMID: 8951084 Review.
The oligomycin sensitivity conferring protein of rat liver mitochondrial ATP synthase: arginine 94 is important for the binding of OSCP to F1.
Golden TR, Pedersen PL. Golden TR, et al. Among authors: pedersen pl. Biochemistry. 1998 Sep 29;37(39):13871-81. doi: 10.1021/bi981120a. Biochemistry. 1998. PMID: 9753477
Delta subunit of rat liver mitochondrial ATP synthase: molecular description and novel insights into the nature of its association with the F1-moiety.
Pan W, Ko YH, Pedersen PL. Pan W, et al. Among authors: pedersen pl. Biochemistry. 1998 May 12;37(19):6911-23. doi: 10.1021/bi9800698. Biochemistry. 1998. PMID: 9578578
Although recently shown to associate tightly with the beta subunit [Pedersen, P. L., Hullihen, J., Bianchet, M., Amzel, L. M., and Lebowitz, M. ...
Although recently shown to associate tightly with the beta subunit [Pedersen, P. L., Hullihen, J., Bianchet, M., Amzel, L. M., and Le …
Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase.
Mathupala SP, Rempel A, Pedersen PL. Mathupala SP, et al. Among authors: pedersen pl. J Bioenerg Biomembr. 1997 Aug;29(4):339-43. doi: 10.1023/a:1022494613613. J Bioenerg Biomembr. 1997. PMID: 9387094 Review.
Novel insights into the chemical mechanism of ATP synthase. Evidence that in the transition state the gamma-phosphate of ATP is near the conserved alanine within the P-loop of the beta-subunit.
Ko YH, Bianchet M, Amzel LM, Pedersen PL. Ko YH, et al. Among authors: pedersen pl. J Biol Chem. 1997 Jul 25;272(30):18875-81. doi: 10.1074/jbc.272.30.18875. J Biol Chem. 1997. PMID: 9228065
Cystic fibrosis transmembrane conductance regulator: the first nucleotide binding fold targets the membrane with retention of its ATP binding function.
Ko YH, Delannoy M, Pedersen PL. Ko YH, et al. Among authors: pedersen pl. Biochemistry. 1997 Apr 22;36(16):5053-64. doi: 10.1021/bi9630265. Biochemistry. 1997. PMID: 9125527
Protein inhibitor of mitochondrial ATP synthase: relationship of inhibitor structure to pH-dependent regulation.
Lebowitz MS, Pedersen PL. Lebowitz MS, et al. Among authors: pedersen pl. Arch Biochem Biophys. 1996 Jun 15;330(2):342-54. doi: 10.1006/abbi.1996.0261. Arch Biochem Biophys. 1996. PMID: 8660664
ATP synthases. Structure, reaction center, mechanism, and regulation of one of nature's most unique machines.
Pedersen PL, Amzel LM. Pedersen PL, et al. J Biol Chem. 1993 May 15;268(14):9937-40. J Biol Chem. 1993. PMID: 8486720 Review. No abstract available.
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