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Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial.
Emery P, Breedveld FC, Hall S, Durez P, Chang DJ, Robertson D, Singh A, Pedersen RD, Koenig AS, Freundlich B. Emery P, et al. Among authors: pedersen rd. Lancet. 2008 Aug 2;372(9636):375-82. doi: 10.1016/S0140-6736(08)61000-4. Epub 2008 Jul 16. Lancet. 2008. PMID: 18635256 Clinical Trial.
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial.
Klareskog L, van der Heijde D, de Jager JP, Gough A, Kalden J, Malaise M, Martín Mola E, Pavelka K, Sany J, Settas L, Wajdula J, Pedersen R, Fatenejad S, Sanda M; TEMPO (Trial of Etanercept and Methotrexate with Radiographic Patient Outcomes) study investigators. Klareskog L, et al. Lancet. 2004 Feb 28;363(9410):675-81. doi: 10.1016/S0140-6736(04)15640-7. Lancet. 2004. PMID: 15001324 Clinical Trial.
Efficacy and safety of combination etanercept and methotrexate versus etanercept alone in patients with rheumatoid arthritis with an inadequate response to methotrexate: the ADORE study.
van Riel PL, Taggart AJ, Sany J, Gaubitz M, Nab HW, Pedersen R, Freundlich B, MacPeek D; Add Enbrel or Replace Methotrexate Study Investigators. van Riel PL, et al. Ann Rheum Dis. 2006 Nov;65(11):1478-83. doi: 10.1136/ard.2005.043299. Epub 2006 Feb 7. Ann Rheum Dis. 2006. PMID: 16464988 Free PMC article. Clinical Trial.
Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial.
van der Heijde D, Klareskog L, Rodriguez-Valverde V, Codreanu C, Bolosiu H, Melo-Gomes J, Tornero-Molina J, Wajdula J, Pedersen R, Fatenejad S; TEMPO Study Investigators. van der Heijde D, et al. Arthritis Rheum. 2006 Apr;54(4):1063-74. doi: 10.1002/art.21655. Arthritis Rheum. 2006. PMID: 16572441 Free article. Clinical Trial.
The safety and efficacy of adding etanercept to methotrexate or methotrexate to etanercept in moderately active rheumatoid arthritis patients previously treated with monotherapy.
van der Heijde D, Burmester G, Melo-Gomes J, Codreanu C, Mola EM, Pedersen R, Freundlich B, Chang DJ; Etanercept Study 400 Investigators. van der Heijde D, et al. Ann Rheum Dis. 2008 Feb;67(2):182-8. doi: 10.1136/ard.2007.076166. Epub 2007 Aug 29. Ann Rheum Dis. 2008. PMID: 17728331 Clinical Trial.
Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis.
van der Heijde D, Klareskog L, Landewé R, Bruyn GA, Cantagrel A, Durez P, Herrero-Beaumont G, Molad Y, Codreanu C, Valentini G, Zahora R, Pedersen R, MacPeek D, Wajdula J, Fatenejad S. van der Heijde D, et al. Arthritis Rheum. 2007 Dec;56(12):3928-39. doi: 10.1002/art.23141. Arthritis Rheum. 2007. PMID: 18050208 Free article. Clinical Trial.
91 results