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Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass.
Gelling RW, Vuguin PM, Du XQ, Cui L, Rømer J, Pederson RA, Leiser M, Sørensen H, Holst JJ, Fledelius C, Johansen PB, Fleischer N, McIntosh CH, Nishimura E, Charron MJ. Gelling RW, et al. Among authors: pederson ra. Am J Physiol Endocrinol Metab. 2009 Sep;297(3):E695-707. doi: 10.1152/ajpendo.00082.2009. Epub 2009 Jul 14. Am J Physiol Endocrinol Metab. 2009. PMID: 19602585 Free PMC article.
Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.
Ehses JA, Casilla VR, Doty T, Pospisilik JA, Winter KD, Demuth HU, Pederson RA, McIntosh CH. Ehses JA, et al. Among authors: pederson ra. Endocrinology. 2003 Oct;144(10):4433-45. doi: 10.1210/en.2002-0068. Epub 2003 Jun 19. Endocrinology. 2003. PMID: 12960055
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