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Purinosome formation as a function of the cell cycle.
Chan CY, Zhao H, Pugh RJ, Pedley AM, French J, Jones SA, Zhuang X, Jinnah H, Huang TJ, Benkovic SJ. Chan CY, et al. Among authors: pedley am. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1368-73. doi: 10.1073/pnas.1423009112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605889 Free PMC article.
Spatial colocalization and functional link of purinosomes with mitochondria.
French JB, Jones SA, Deng H, Pedley AM, Kim D, Chan CY, Hu H, Pugh RJ, Zhao H, Zhang Y, Huang TJ, Fang Y, Zhuang X, Benkovic SJ. French JB, et al. Among authors: pedley am. Science. 2016 Feb 12;351(6274):733-7. doi: 10.1126/science.aac6054. Science. 2016. PMID: 26912862 Free PMC article.
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis.
Pedley AM, Karras GI, Zhang X, Lindquist S, Benkovic SJ. Pedley AM, et al. Biochemistry. 2018 Jun 12;57(23):3217-3221. doi: 10.1021/acs.biochem.8b00140. Epub 2018 Mar 23. Biochemistry. 2018. PMID: 29553718 Free PMC article.
Hypoxia drives the assembly of the multienzyme purinosome complex.
Doigneaux C, Pedley AM, Mistry IN, Papayova M, Benkovic SJ, Tavassoli A. Doigneaux C, et al. Among authors: pedley am. J Biol Chem. 2020 Jul 10;295(28):9551-9566. doi: 10.1074/jbc.RA119.012175. Epub 2020 May 21. J Biol Chem. 2020. PMID: 32439803 Free PMC article.
Human de novo purine biosynthesis.
Pareek V, Pedley AM, Benkovic SJ. Pareek V, et al. Among authors: pedley am. Crit Rev Biochem Mol Biol. 2021 Feb;56(1):1-16. doi: 10.1080/10409238.2020.1832438. Epub 2020 Nov 12. Crit Rev Biochem Mol Biol. 2021. PMID: 33179964
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