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Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression.
Raposinho PD, Pedrazzini T, White RB, Palmiter RD, Aubert ML. Raposinho PD, et al. Among authors: pedrazzini t. Endocrinology. 2004 Jan;145(1):304-10. doi: 10.1210/en.2003-0914. Epub 2003 Oct 2. Endocrinology. 2004. PMID: 14525913
Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization.
Kopp J, Xu ZQ, Zhang X, Pedrazzini T, Herzog H, Kresse A, Wong H, Walsh JH, Hökfelt T. Kopp J, et al. Among authors: pedrazzini t. Neuroscience. 2002;111(3):443-532. doi: 10.1016/s0306-4522(01)00463-8. Neuroscience. 2002. PMID: 12031341
The neuropeptide Y Y1 receptor mediates NPY-induced inhibition of the gonadotrope axis under poor metabolic conditions.
Gonzales C, Voirol MJ, Giacomini M, Gaillard RC, Pedrazzini T, Pralong FP. Gonzales C, et al. Among authors: pedrazzini t. FASEB J. 2004 Jan;18(1):137-9. doi: 10.1096/fj.03-0189fje. Epub 2003 Nov 3. FASEB J. 2004. PMID: 14597564
Importance of NPY Y1 receptor-mediated pathways: assessment using NPY Y1 receptor knockouts.
Pedrazzini T. Pedrazzini T. Neuropeptides. 2004 Aug;38(4):267-75. doi: 10.1016/j.npep.2004.05.007. Neuropeptides. 2004. PMID: 15337379 Review.
The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions.
Pralong FP, Gonzales C, Voirol MJ, Palmiter RD, Brunner HR, Gaillard RC, Seydoux J, Pedrazzini T. Pralong FP, et al. Among authors: pedrazzini t. FASEB J. 2002 May;16(7):712-4. doi: 10.1096/fj.01-0754fje. Epub 2002 Mar 12. FASEB J. 2002. PMID: 11978737
Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion.
Cavadas C, Céfai D, Rosmaninho-Salgado J, Vieira-Coelho MA, Moura E, Busso N, Pedrazzini T, Grand D, Rotman S, Waeber B, Aubert JF, Grouzmann E. Cavadas C, et al. Among authors: pedrazzini t. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10497-10502. doi: 10.1073/pnas.0600913103. Epub 2006 Jun 23. Proc Natl Acad Sci U S A. 2006. PMID: 16798884 Free PMC article.
Increased insulin concentrations and glucose storage in neuropeptide Y Y1 receptor-deficient mice.
Burcelin R, Brunner H, Seydoux J, Thorensa B, Pedrazzini T. Burcelin R, et al. Among authors: pedrazzini t. Peptides. 2001 Mar;22(3):421-7. doi: 10.1016/s0196-9781(01)00357-6. Peptides. 2001. PMID: 11287097
Neuropeptide Y Y1 receptor-deficient mice. Generation and characterization.
Pedrazzini T, Seydoux J. Pedrazzini T, et al. Methods Mol Biol. 2000;153:91-100. doi: 10.1385/1-59259-042-X:91. Methods Mol Biol. 2000. PMID: 10957987 No abstract available.
Neuropeptide Y (NPY) potentiates phenylephrine-induced mitogen-activated protein kinase activation in primary cardiomyocytes via NPY Y5 receptors.
Pellieux C, Sauthier T, Domenighetti A, Marsh DJ, Palmiter RD, Brunner HR, Pedrazzini T. Pellieux C, et al. Among authors: pedrazzini t. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1595-600. doi: 10.1073/pnas.030533197. Proc Natl Acad Sci U S A. 2000. PMID: 10660688 Free PMC article.
Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor.
Pedrazzini T, Seydoux J, Künstner P, Aubert JF, Grouzmann E, Beermann F, Brunner HR. Pedrazzini T, et al. Nat Med. 1998 Jun;4(6):722-6. doi: 10.1038/nm0698-722. Nat Med. 1998. PMID: 9623984
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