Pegg AE - Search Results

1

Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents.

Dolan ME, Corsico CD, Pegg AE. Dolan ME, et al. Among authors: pegg ae. Biochem Biophys Res Commun. 1985 Oct 15;132(1):178-85. doi: 10.1016/0006-291x(85)91004-6. Biochem Biophys Res Commun. 1985. PMID: 4062928

2

Formation and subsequent removal of O6-methylguanine from deoxyribonucleic acid in rat liver and kidney after small doses of dimethylnitrosamine.

Pegg AE, Hui G. Pegg AE, et al. Biochem J. 1978 Sep 1;173(3):739-48. doi: 10.1042/bj1730739. Biochem J. 1978. PMID: 708371 Free PMC article.

3

Polyamine depletion inhibits the differentiation of L6 myoblast cells.

Erwin BG, Ewton DZ, Florini JR, Pegg AE. Erwin BG, et al. Among authors: pegg ae. Biochem Biophys Res Commun. 1983 Aug 12;114(3):944-9. doi: 10.1016/0006-291x(83)90651-4. Biochem Biophys Res Commun. 1983. PMID: 6412710

4

Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.

Dolan ME, Mitchell RB, Mummert C, Moschel RC, Pegg AE. Dolan ME, et al. Among authors: pegg ae. Cancer Res. 1991 Jul 1;51(13):3367-72. Cancer Res. 1991. PMID: 1647266

5

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents.

Pegg AE. Pegg AE. Cancer Res. 1990 Oct 1;50(19):6119-29. Cancer Res. 1990. PMID: 2205376 Review. No abstract available.

6

Alkylation damage repair protein O6-alkylguanine-DNA alkyltransferase from the hyperthermophiles Aquifex aeolicus and Archaeoglobus fulgidus.

Kanugula S, Pegg AE. Kanugula S, et al. Among authors: pegg ae. Biochem J. 2003 Oct 15;375(Pt 2):449-55. doi: 10.1042/BJ20030809. Biochem J. 2003. PMID: 12892560 Free PMC article.

7

Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.

Ikeguchi Y, Mackintosh CA, McCloskey DE, Pegg AE. Ikeguchi Y, et al. Among authors: pegg ae. Biochem J. 2003 Aug 1;373(Pt 3):885-92. doi: 10.1042/BJ20030246. Biochem J. 2003. PMID: 12737625 Free PMC article.

8

Interaction of mammalian O(6)-alkylguanine-DNA alkyltransferases with O(6)-benzylguanine.

Loktionova NA, Pegg AE. Loktionova NA, et al. Among authors: pegg ae. Biochem Pharmacol. 2002 Apr 15;63(8):1431-42. doi: 10.1016/s0006-2952(02)00906-1. Biochem Pharmacol. 2002. PMID: 11996884

9

Effect of N-(n-butyl)-1,3-diaminopropane on polyamine metabolism, cell growth and sensitivity to chloroethylating agents.

Pegg AE, Coward JK. Pegg AE, et al. Biochem Pharmacol. 1993 Aug 17;46(4):717-24. doi: 10.1016/0006-2952(93)90559-f. Biochem Pharmacol. 1993. PMID: 8395844

10

Point mutations at multiple sites including highly conserved amino acids maintain activity, but render O6-alkylguanine-DNA alkyltransferase insensitive to O6-benzylguanine.

Xu-Welliver M, Pegg AE. Xu-Welliver M, et al. Among authors: pegg ae. Biochem J. 2000 Apr 15;347(Pt 2):519-26. doi: 10.1042/0264-6021:3470519. Biochem J. 2000. PMID: 10749682 Free PMC article.

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