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Transcriptional regulation of cadherins during development and carcinogenesis.
Peinado H, Portillo F, Cano A. Peinado H, et al. Int J Dev Biol. 2004;48(5-6):365-75. doi: 10.1387/ijdb.041794hp. Int J Dev Biol. 2004. PMID: 15349812 Review.
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors.
Bolós V, Peinado H, Pérez-Moreno MA, Fraga MF, Esteller M, Cano A. Bolós V, et al. J Cell Sci. 2003 Feb 1;116(Pt 3):499-511. doi: 10.1242/jcs.00224. J Cell Sci. 2003. PMID: 12508111
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.
Peinado H, Quintanilla M, Cano A. Peinado H, et al. J Biol Chem. 2003 Jun 6;278(23):21113-23. doi: 10.1074/jbc.M211304200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665527
Interestingly, TGFbeta1-mediated induction of Snail promoter is blocked by a dominant negative form of H-Ras (N17Ras), whereas oncogenic H-Ras (V12Ras) induces Snail promoter activity and synergistically cooperates with TGFbeta1. ...In addition, H-Ras-mediate …
Interestingly, TGFbeta1-mediated induction of Snail promoter is blocked by a dominant negative form of H-Ras (N17Ras), whereas oncoge …
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors.
Fraga MF, Herranz M, Espada J, Ballestar E, Paz MF, Ropero S, Erkek E, Bozdogan O, Peinado H, Niveleau A, Mao JH, Balmain A, Cano A, Esteller M. Fraga MF, et al. Cancer Res. 2004 Aug 15;64(16):5527-34. doi: 10.1158/0008-5472.CAN-03-4061. Cancer Res. 2004. PMID: 15313885
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression.
Peinado H, Del Carmen Iglesias-de la Cruz M, Olmeda D, Csiszar K, Fong KS, Vega S, Nieto MA, Cano A, Portillo F. Peinado H, et al. EMBO J. 2005 Oct 5;24(19):3446-58. doi: 10.1038/sj.emboj.7600781. Epub 2005 Aug 18. EMBO J. 2005. PMID: 16096638 Free PMC article.
Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis.
Millán O, Rico D, Peinado H, Zarich N, Stamatakis K, Pérez-Sala D, Rojas JM, Cano A, Boscá L. Millán O, et al. Carcinogenesis. 2006 Feb;27(2):328-36. doi: 10.1093/carcin/bgi213. Epub 2005 Aug 19. Carcinogenesis. 2006. PMID: 16113051
Switching on-off Snail: LOXL2 versus GSK3beta.
Peinado H, Portillo F, Cano A. Peinado H, et al. Cell Cycle. 2005 Dec;4(12):1749-52. doi: 10.4161/cc.4.12.2224. Epub 2005 Dec 5. Cell Cycle. 2005. PMID: 16294032
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