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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
Peinado H, Olmeda D, Cano A. Peinado H, et al. Nat Rev Cancer. 2007 Jun;7(6):415-28. doi: 10.1038/nrc2131. Epub 2007 May 17. Nat Rev Cancer. 2007. PMID: 17508028 Review.
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors.
Bolós V, Peinado H, Pérez-Moreno MA, Fraga MF, Esteller M, Cano A. Bolós V, et al. Among authors: peinado h. J Cell Sci. 2003 Feb 1;116(Pt 3):499-511. doi: 10.1242/jcs.00224. J Cell Sci. 2003. PMID: 12508111
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.
Peinado H, Quintanilla M, Cano A. Peinado H, et al. J Biol Chem. 2003 Jun 6;278(23):21113-23. doi: 10.1074/jbc.M211304200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665527
Interestingly, TGFbeta1-mediated induction of Snail promoter is blocked by a dominant negative form of H-Ras (N17Ras), whereas oncogenic H-Ras (V12Ras) induces Snail promoter activity and synergistically cooperates with TGFbeta1. ...In addition, H-Ras-mediate …
Interestingly, TGFbeta1-mediated induction of Snail promoter is blocked by a dominant negative form of H-Ras (N17Ras), whereas oncoge …
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex.
Peinado H, Ballestar E, Esteller M, Cano A. Peinado H, et al. Mol Cell Biol. 2004 Jan;24(1):306-19. doi: 10.1128/mcb.24.1.306-319.2004. Mol Cell Biol. 2004. PMID: 14673164 Free PMC article.
Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo.
Peinado H, Marin F, Cubillo E, Stark HJ, Fusenig N, Nieto MA, Cano A. Peinado H, et al. J Cell Sci. 2004 Jun 1;117(Pt 13):2827-39. doi: 10.1242/jcs.01145. J Cell Sci. 2004. PMID: 15169839
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors.
Fraga MF, Herranz M, Espada J, Ballestar E, Paz MF, Ropero S, Erkek E, Bozdogan O, Peinado H, Niveleau A, Mao JH, Balmain A, Cano A, Esteller M. Fraga MF, et al. Among authors: peinado h. Cancer Res. 2004 Aug 15;64(16):5527-34. doi: 10.1158/0008-5472.CAN-03-4061. Cancer Res. 2004. PMID: 15313885
Transcriptional regulation of cadherins during development and carcinogenesis.
Peinado H, Portillo F, Cano A. Peinado H, et al. Int J Dev Biol. 2004;48(5-6):365-75. doi: 10.1387/ijdb.041794hp. Int J Dev Biol. 2004. PMID: 15349812 Review.
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression.
Peinado H, Del Carmen Iglesias-de la Cruz M, Olmeda D, Csiszar K, Fong KS, Vega S, Nieto MA, Cano A, Portillo F. Peinado H, et al. EMBO J. 2005 Oct 5;24(19):3446-58. doi: 10.1038/sj.emboj.7600781. Epub 2005 Aug 18. EMBO J. 2005. PMID: 16096638 Free PMC article.
The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells.
Martínez-Estrada OM, Cullerés A, Soriano FX, Peinado H, Bolós V, Martínez FO, Reina M, Cano A, Fabre M, Vilaró S. Martínez-Estrada OM, et al. Among authors: peinado h. Biochem J. 2006 Mar 1;394(Pt 2):449-57. doi: 10.1042/BJ20050591. Biochem J. 2006. PMID: 16232121 Free PMC article.
Switching on-off Snail: LOXL2 versus GSK3beta.
Peinado H, Portillo F, Cano A. Peinado H, et al. Cell Cycle. 2005 Dec;4(12):1749-52. doi: 10.4161/cc.4.12.2224. Epub 2005 Dec 5. Cell Cycle. 2005. PMID: 16294032
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