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187 results

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Page 1
Unlocking the therapeutic potential of Pelargonium sidoides natural extract: A scoping review.
Reina BD, Malheiros SS, Vieira SM, Ferreira de Andrade P, Dovigo LN. Reina BD, et al. Heliyon. 2024 Nov 20;10(23):e40554. doi: 10.1016/j.heliyon.2024.e40554. eCollection 2024 Dec 15. Heliyon. 2024. PMID: 39654721 Free PMC article.
Pelargonium sidoides DC. (Geraniaceae) is a widely recognized medicinal plant whose natural extract exhibits therapeutic effects through a multi-target approach. ...A systematic search of Medline (PubMED) and Scopus databases was conducted using the terms: EPs7630, …
Pelargonium sidoides DC. (Geraniaceae) is a widely recognized medicinal plant whose natural extract exhibits therapeutic effec …
Pelargonium sidoides extract mediates nephrotoxicity through mitochondrial malfunction and cytoskeleton destabilization.
Lee JY, Lee J, Lee SH, Hwang JH, Suh HN. Lee JY, et al. Toxicol Res. 2023 May 27;39(4):601-609. doi: 10.1007/s43188-023-00186-0. eCollection 2023 Oct. Toxicol Res. 2023. PMID: 37779585 Free PMC article.
We investigated the cytotoxic effect of Pelargonium sidoides extract on Madin-Darby canine kidney (MDCK) cells. P. sidoides extract decreased the cell viability in a dose dependent manner (> 0.2%). ...NAC or RhoA/Rac1/cdc42 activator pretreatment reduced P …
We investigated the cytotoxic effect of Pelargonium sidoides extract on Madin-Darby canine kidney (MDCK) cells. P. sidoides …
Pelargonium sidoides extract EPs 7630: a review of its clinical efficacy and safety for treating acute respiratory tract infections in children.
Careddu D, Pettenazzo A. Careddu D, et al. Int J Gen Med. 2018 Mar 8;11:91-98. doi: 10.2147/IJGM.S154198. eCollection 2018. Int J Gen Med. 2018. PMID: 29563828 Free PMC article. Review.
BACKGROUND: In numerous randomized controlled trials (RCTs) and systematic reviews such as those published by the Cochrane Collaboration, Pelargonium sidoides extract EPs( ) 7630 was shown to be effective in acute respiratory tract infections (aRTI) in all investiga …
BACKGROUND: In numerous randomized controlled trials (RCTs) and systematic reviews such as those published by the Cochrane Collaboration, …
Immunomodulatory Effects of Pelargonium sidoides Extract (EPs7630) in the Treatment of Acute Rhinosinusitis.
Perić A, Vezmar Kovačević S, Barać A, Perić A, Vojvodić D. Perić A, et al. Expert Rev Mol Med. 2025 Jul 15;27:e25. doi: 10.1017/erm.2025.10013. Expert Rev Mol Med. 2025. PMID: 40660733 Free PMC article. Review.
BACKGROUND: In this short narrative review, we would like to discuss the immunomodulatory effects of South African geranium (Pelargonium sidoides) root extract EPs7630 in treating acute rhinosinusitis. The plant has been used for centuries to treat respiratory tract …
BACKGROUND: In this short narrative review, we would like to discuss the immunomodulatory effects of South African geranium (Pelargonium …
Pelargonium sidoides extract for acute respiratory tract infections.
Timmer A, Günther J, Rücker G, Motschall E, Antes G, Kern WV. Timmer A, et al. Cochrane Database Syst Rev. 2008 Jul 16;(3):CD006323. doi: 10.1002/14651858.CD006323.pub2. Cochrane Database Syst Rev. 2008. Update in: Cochrane Database Syst Rev. 2013 Oct 22;(10):CD006323. doi: 10.1002/14651858.CD006323.pub3. PMID: 18646148 Updated.
BACKGROUND: Pelargonium sidoides (P. sidoides), also known as Umckaloabo, is a herbal remedy thought to be effective in the treatment of acute respiratory infections (ARIs). ...Adverse events were more common with P. sidoides, but none were serious. AU …
BACKGROUND: Pelargonium sidoides (P. sidoides), also known as Umckaloabo, is a herbal remedy thought to be effective in …
Medicinal properties and conservation of Pelargonium sidoides DC.
Moyo M, Van Staden J. Moyo M, et al. J Ethnopharmacol. 2014 Mar 14;152(2):243-55. doi: 10.1016/j.jep.2014.01.009. Epub 2014 Jan 21. J Ethnopharmacol. 2014. PMID: 24463034 Free PMC article. Review.
The increasing international demand for Pelargonium sidoides has led to localised overexploitation of its wild populations in southern Africa. ...On the other hand, the increasing demand for Pelargonium sidoides has led to localised illegal harvesting …
The increasing international demand for Pelargonium sidoides has led to localised overexploitation of its wild populations in …
Pelargonium sidoides extract for treating acute respiratory tract infections.
Timmer A, Günther J, Motschall E, Rücker G, Antes G, Kern WV. Timmer A, et al. Cochrane Database Syst Rev. 2013 Oct 22;2013(10):CD006323. doi: 10.1002/14651858.CD006323.pub3. Cochrane Database Syst Rev. 2013. PMID: 24146345 Free PMC article.
BACKGROUND: Pelargonium sidoides (P. sidoides), also known as Umckaloabo, is a herbal remedy thought to be effective in the treatment of acute respiratory infections (ARIs). ...Adverse events were more common with P. sidoides, but none were serious. AU …
BACKGROUND: Pelargonium sidoides (P. sidoides), also known as Umckaloabo, is a herbal remedy thought to be effective in …
Pelargonium sidoides - from ethnopharmacology to evidence-based medicine: a systematic review.
Honchar O, Мykhailenko O, Holovchenko O, Georgiyants V. Honchar O, et al. Phytomedicine. 2026 Apr;153:157880. doi: 10.1016/j.phymed.2026.157880. Epub 2026 Jan 23. Phytomedicine. 2026. PMID: 41653615 Review.
BACKGROUND: Pelargonium sidoides DC. (Geraniaceae) has a long history of traditional use among indigenous peoples of Southern Africa for treating respiratory and gastrointestinal disorders. ...PURPOSE: To provide a systematic analysis of P. sidoides, spanning …
BACKGROUND: Pelargonium sidoides DC. (Geraniaceae) has a long history of traditional use among indigenous peoples of Southern …
Pelargonium sidoides for acute bronchitis: a systematic review and meta-analysis.
Agbabiaka TB, Guo R, Ernst E. Agbabiaka TB, et al. Phytomedicine. 2008 May;15(5):378-85. doi: 10.1016/j.phymed.2007.11.023. Epub 2008 Jan 28. Phytomedicine. 2008. PMID: 18222667
OBJECTIVE: To critically assess the efficacy of Pelargonium sidoides for treating acute bronchitis. DATA SOURCES: Systematic literature searches were performed in 5 electronic databases: (Medline (1950 - July 2007), Amed (1985 - July 2007), Embase (1974 - July 2007) …
OBJECTIVE: To critically assess the efficacy of Pelargonium sidoides for treating acute bronchitis. DATA SOURCES: Systematic l …
Interaction of Pelargonium sidoides Compounds with Lactoferrin and SARS-CoV-2: Insights from Molecular Simulations.
Iacovelli F, Costanza G, Romeo A, Cosio T, Lanna C, Bagnulo A, Di Maio U, Sbardella A, Gaziano R, Grelli S, Squillaci E, Miani A, Piscitelli P, Bianchi L, Falconi M, Campione E. Iacovelli F, et al. Int J Environ Res Public Health. 2022 Apr 26;19(9):5254. doi: 10.3390/ijerph19095254. Int J Environ Res Public Health. 2022. PMID: 35564648 Free PMC article.
(1) Background: Pelargonium sidoides extracts and lactoferrin are two important natural, anti-inflammatory, and antiviral agents, which can interfere with the early stages of SARS-CoV-2 infection. ...Furthermore, Pelargonium sidoides compounds should h …
(1) Background: Pelargonium sidoides extracts and lactoferrin are two important natural, anti-inflammatory, and antiviral agen …
187 results