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There is a steady-state transcriptome in exponentially growing yeast cells.
Pelechano V, Pérez-Ortín JE. Pelechano V, et al. Yeast. 2010 Jul;27(7):413-22. doi: 10.1002/yea.1768. Yeast. 2010. PMID: 20301094
Dynamic remodeling of histone modifications in response to osmotic stress in Saccharomyces cerevisiae.
Magraner-Pardo L, Pelechano V, Coloma MD, Tordera V. Magraner-Pardo L, et al. Among authors: pelechano v. BMC Genomics. 2014 Mar 30;15(1):247. doi: 10.1186/1471-2164-15-247. BMC Genomics. 2014. PMID: 24678875 Free PMC article.
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.
Jordán-Pla A, Gupta I, de Miguel-Jiménez L, Steinmetz LM, Chávez S, Pelechano V, Pérez-Ortín JE. Jordán-Pla A, et al. Among authors: pelechano v. Nucleic Acids Res. 2015 Jan;43(2):787-802. doi: 10.1093/nar/gku1349. Epub 2014 Dec 29. Nucleic Acids Res. 2015. PMID: 25550430 Free PMC article.
eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences.
Pelechano V, Alepuz P. Pelechano V, et al. Nucleic Acids Res. 2017 Jul 7;45(12):7326-7338. doi: 10.1093/nar/gkx479. Nucleic Acids Res. 2017. PMID: 28549188 Free PMC article.
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.
García-Martínez J, Delgado-Ramos L, Ayala G, Pelechano V, Medina DA, Carrasco F, González R, Andrés-León E, Steinmetz L, Warringer J, Chávez S, Pérez-Ortín JE. García-Martínez J, et al. Among authors: pelechano v. Nucleic Acids Res. 2016 May 5;44(8):3643-58. doi: 10.1093/nar/gkv1512. Epub 2015 Dec 29. Nucleic Acids Res. 2016. PMID: 26717982 Free PMC article.
Biotin-Genomic Run-On (Bio-GRO): A High-Resolution Method for the Analysis of Nascent Transcription in Yeast.
Jordán-Pla A, Miguel A, Serna E, Pelechano V, Pérez-Ortín JE. Jordán-Pla A, et al. Among authors: pelechano v. Methods Mol Biol. 2016;1361:125-39. doi: 10.1007/978-1-4939-3079-1_8. Methods Mol Biol. 2016. PMID: 26483020
The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast.
García-Martínez J, Ayala G, Pelechano V, Chávez S, Herrero E, Pérez-Ortín JE. García-Martínez J, et al. Among authors: pelechano v. Transcription. 2012 Jan-Feb;3(1):39-44. doi: 10.4161/trns.3.1.19416. Transcription. 2012. PMID: 22456320 Free PMC article.
The conserved foot domain of RNA pol II associates with proteins involved in transcriptional initiation and/or early elongation.
García-López MC, Pelechano V, Mirón-García MC, Garrido-Godino AI, García A, Calvo O, Werner M, Pérez-Ortín JE, Navarro F. García-López MC, et al. Among authors: pelechano v. Genetics. 2011 Dec;189(4):1235-48. doi: 10.1534/genetics.111.133215. Epub 2011 Sep 27. Genetics. 2011. PMID: 21954159 Free PMC article.
A genomic view of mRNA turnover in yeast.
Pérez-Ortín JE, Jordán-Pla A, Pelechano V. Pérez-Ortín JE, et al. Among authors: pelechano v. C R Biol. 2011 Aug-Sep;334(8-9):647-54. doi: 10.1016/j.crvi.2011.05.013. Epub 2011 Jul 5. C R Biol. 2011. PMID: 21819946 Review.
Genomic-wide methods to evaluate transcription rates in yeast.
García-Martínez J, Pelechano V, Pérez-Ortín JE. García-Martínez J, et al. Among authors: pelechano v. Methods Mol Biol. 2011;734:25-44. doi: 10.1007/978-1-61779-086-7_2. Methods Mol Biol. 2011. PMID: 21468983
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