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Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Wei J, Kitada S, Stebbins JL, Placzek W, Zhai D, Wu B, Rega MF, Zhang Z, Cellitti J, Yang L, Dahl R, Reed JC, Pellecchia M. Wei J, et al. Among authors: pellecchia m. J Med Chem. 2010 Nov 25;53(22):8000-11. doi: 10.1021/jm100746q. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033669 Free PMC article.
Structure-based discovery of a new class of Bcl-xL antagonists.
Rega MF, Leone M, Jung D, Cotton NJ, Stebbins JL, Pellecchia M. Rega MF, et al. Among authors: pellecchia m. Bioorg Chem. 2007 Aug;35(4):344-53. doi: 10.1016/j.bioorg.2007.03.001. Epub 2007 May 21. Bioorg Chem. 2007. PMID: 17512966 Free PMC article.
Discovery and binding studies on a series of novel Pin1 ligands.
Wu B, Rega MF, Wei J, Yuan H, Dahl R, Zhang Z, Pellecchia M. Wu B, et al. Among authors: pellecchia m. Chem Biol Drug Des. 2009 Apr;73(4):369-79. doi: 10.1111/j.1747-0285.2009.00795.x. Chem Biol Drug Des. 2009. PMID: 19291099 Free PMC article.
459 results