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Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer.
Lo T, Pellegrini L, Venkitaraman AR, Blundell TL. Lo T, et al. DNA Repair (Amst). 2003 Sep 18;2(9):1015-28. doi: 10.1016/s1568-7864(03)00097-1. DNA Repair (Amst). 2003. PMID: 12967658
A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome.
Kilkenny ML, De Piccoli G, Perera RL, Labib K, Pellegrini L. Kilkenny ML, et al. J Biol Chem. 2012 Jul 6;287(28):23740-7. doi: 10.1074/jbc.M112.368951. Epub 2012 May 16. J Biol Chem. 2012. PMID: 22593576 Free PMC article.
A molecular model for the role of SYCP3 in meiotic chromosome organisation.
Syrjänen JL, Pellegrini L, Davies OR. Syrjänen JL, et al. Elife. 2014 Jun 20;3:e02963. doi: 10.7554/eLife.02963. Elife. 2014. PMID: 24950965 Free PMC article.
Structural basis for inhibition of homologous recombination by the RecX protein.
Ragone S, Maman JD, Furnham N, Pellegrini L. Ragone S, et al. EMBO J. 2008 Aug 20;27(16):2259-69. doi: 10.1038/emboj.2008.145. Epub 2008 Jul 24. EMBO J. 2008. PMID: 18650935 Free PMC article.
Structure of human Cdc45 and implications for CMG helicase function.
Simon AC, Sannino V, Costanzo V, Pellegrini L. Simon AC, et al. Nat Commun. 2016 May 18;7:11638. doi: 10.1038/ncomms11638. Nat Commun. 2016. PMID: 27189187 Free PMC article.
Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.
Wu Y, Villa F, Maman J, Lau YH, Dobnikar L, Simon AC, Labib K, Spring DR, Pellegrini L. Wu Y, et al. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12866-12872. doi: 10.1002/anie.201705611. Epub 2017 Sep 7. Angew Chem Int Ed Engl. 2017. PMID: 28815832
Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA.
Brouwer I, Moschetti T, Candelli A, Garcin EB, Modesti M, Pellegrini L, Wuite GJ, Peterman EJ. Brouwer I, et al. EMBO J. 2018 Apr 3;37(7):e98162. doi: 10.15252/embj.201798162. Epub 2018 Mar 5. EMBO J. 2018. PMID: 29507080 Free PMC article.
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