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Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis.
Valenti L, Maggioni P, Piperno A, Rametta R, Pelucchi S, Mariani R, Dongiovanni P, Fracanzani AL, Fargion S. Valenti L, et al. Among authors: Pelucchi S. World J Gastroenterol. 2012 Jun 14;18(22):2813-20. doi: 10.3748/wjg.v18.i22.2813. World J Gastroenterol. 2012. PMID: 22719190 Free PMC article.
Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis.
de Tayrac M, Roth MP, Jouanolle AM, Coppin H, le Gac G, Piperno A, Férec C, Pelucchi S, Scotet V, Bardou-Jacquet E, Ropert M, Bouvet R, Génin E, Mosser J, Deugnier Y. de Tayrac M, et al. Among authors: Pelucchi S. J Hepatol. 2015 Mar;62(3):664-72. doi: 10.1016/j.jhep.2014.10.017. Epub 2014 Oct 18. J Hepatol. 2015. PMID: 25457201 Clinical Trial.
Patients with chronic hepatitis C may be more sensitive to iron hepatotoxicity than patients with HFE-hemochromatosis.
Hayashi H, Piperno A, Tomosugi N, Hayashi K, Kimura F, Wakusawa S, Yano M, Tatsumi Y, Hattori A, Pelucchi S, Katano Y, Goto H. Hayashi H, et al. Among authors: Pelucchi S. Intern Med. 2010;49(22):2371-7. doi: 10.2169/internalmedicine.49.4088. Epub 2010 Nov 15. Intern Med. 2010. PMID: 21088336
Hepcidin expression in iron overload diseases is variably modulated by circulating factors.
Ravasi G, Pelucchi S, Trombini P, Mariani R, Tomosugi N, Modignani GL, Pozzi M, Nemeth E, Ganz T, Hayashi H, Barisani D, Piperno A. Ravasi G, et al. Among authors: Pelucchi S. PLoS One. 2012;7(5):e36425. doi: 10.1371/journal.pone.0036425. Epub 2012 May 7. PLoS One. 2012. PMID: 22586470 Free PMC article.
Measurement of serum hepcidin-25 levels as a potential test for diagnosing hemochromatosis and related disorders.
Kaneko Y, Miyajima H, Piperno A, Tomosugi N, Hayashi H, Morotomi N, Tsuchida K, Ikeda T, Ishikawa A, Ota Y, Wakusawa S, Yoshioka K, Kono S, Pelucchi S, Hattori A, Tatsumi Y, Okada T, Yamagishi M. Kaneko Y, et al. Among authors: Pelucchi S. J Gastroenterol. 2010 Nov;45(11):1163-71. doi: 10.1007/s00535-010-0259-8. Epub 2010 Jun 9. J Gastroenterol. 2010. PMID: 20533066
A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis.
Girelli D, Trombini P, Busti F, Campostrini N, Sandri M, Pelucchi S, Westerman M, Ganz T, Nemeth E, Piperno A, Camaschella C. Girelli D, et al. Among authors: Pelucchi S. Haematologica. 2011 Apr;96(4):500-6. doi: 10.3324/haematol.2010.033449. Epub 2010 Dec 20. Haematologica. 2011. PMID: 21173098 Free PMC article.
Type 3 hemochromatosis and beta-thalassemia trait.
Riva A, Mariani R, Bovo G, Pelucchi S, Arosio C, Salvioni A, Vergani A, Piperno A. Riva A, et al. Among authors: Pelucchi S. Eur J Haematol. 2004 May;72(5):370-4. doi: 10.1111/j.1600-0609.2004.00230.x. Eur J Haematol. 2004. PMID: 15059075
Liver biopsies, performed at the age of 34 and 49 yr, indicate that in type 3 hemochromatosis there is a progressive hepatocellular iron accumulation from Rappaport's zone 1-3 and that iron loading in sinusoidal and portal macrophages occurs only in the more advanced stage. ...
Liver biopsies, performed at the age of 34 and 49 yr, indicate that in type 3 hemochromatosis there is a progressive hepatocellular iron acc …
[PubMed: 31153447]
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