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NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
Pessentheiner AR, Pelzmann HJ, Walenta E, Schweiger M, Groschner LN, Graier WF, Kolb D, Uno K, Miyazaki T, Nitta A, Rieder D, Prokesch A, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: pelzmann hj. J Biol Chem. 2013 Dec 13;288(50):36040-51. doi: 10.1074/jbc.M113.491324. Epub 2013 Oct 23. J Biol Chem. 2013. PMID: 24155240 Free PMC article.
N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Prokesch A, Pelzmann HJ, Pessentheiner AR, Huber K, Madreiter-Sokolowski CT, Drougard A, Schittmayer M, Kolb D, Magnes C, Trausinger G, Graier WF, Birner-Gruenberger R, Pospisilik JA, Bogner-Strauss JG. Prokesch A, et al. Among authors: pelzmann hj. Sci Rep. 2016 Apr 5;6:23723. doi: 10.1038/srep23723. Sci Rep. 2016. PMID: 27045997 Free PMC article.
N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
Huber K, Hofer DC, Trefely S, Pelzmann HJ, Madreiter-Sokolowski C, Duta-Mare M, Schlager S, Trausinger G, Stryeck S, Graier WF, Kolb D, Magnes C, Snyder NW, Prokesch A, Kratky D, Madl T, Wellen KE, Bogner-Strauss JG. Huber K, et al. Among authors: pelzmann hj. Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):337-348. doi: 10.1016/j.bbamcr.2018.08.017. Epub 2018 Aug 31. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30595160 Free PMC article.
Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.
Hofer DC, Pessentheiner AR, Pelzmann HJ, Schlager S, Madreiter-Sokolowski CT, Kolb D, Eichmann TO, Rechberger G, Bilban M, Graier WF, Kratky D, Bogner-Strauss JG. Hofer DC, et al. Among authors: pelzmann hj. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Mar;1862(3):358-368. doi: 10.1016/j.bbalip.2016.12.009. Epub 2016 Dec 23. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28017862 Free PMC article.
APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
Pessentheiner AR, Huber K, Pelzmann HJ, Prokesch A, Radner FPW, Wolinski H, Lindroos-Christensen J, Hoefler G, Rülicke T, Birner-Gruenberger R, Bilban M, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: pelzmann hj. FASEB J. 2017 Sep;31(9):4088-4103. doi: 10.1096/fj.201601337R. Epub 2017 May 30. FASEB J. 2017. PMID: 28559441 Free PMC article.
N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
Hofer DC, Zirkovits G, Pelzmann HJ, Huber K, Pessentheiner AR, Xia W, Uno K, Miyazaki T, Kon K, Tsuneki H, Pendl T, Zoughbi WA, Madreiter-Sokolowski CT, Trausinger G, Abdellatif M, Schoiswohl G, Schreiber R, Eisenberg T, Magnes C, Sedej S, Eckhardt M, Sasahara M, Sasaoka T, Nitta A, Hoefler G, Graier WF, Kratky D, Auwerx J, Bogner-Strauss JG. Hofer DC, et al. Among authors: pelzmann hj. FASEB J. 2019 Dec;33(12):13808-13824. doi: 10.1096/fj.201801323R. Epub 2019 Nov 1. FASEB J. 2019. PMID: 31638418 Free PMC article.