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Signalling pathways regulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway.
Sandri M, Barberi L, Bijlsma AY, Blaauw B, Dyar KA, Milan G, Mammucari C, Meskers CG, Pallafacchina G, Paoli A, Pion D, Roceri M, Romanello V, Serrano AL, Toniolo L, Larsson L, Maier AB, Muñoz-Cánoves P, Musarò A, Pende M, Reggiani C, Rizzuto R, Schiaffino S. Sandri M, et al. Among authors: pende m. Biogerontology. 2013 Jun;14(3):303-23. doi: 10.1007/s10522-013-9432-9. Epub 2013 May 19. Biogerontology. 2013. PMID: 23686362
S6K1 Is Required for Increasing Skeletal Muscle Force during Hypertrophy.
Marabita M, Baraldo M, Solagna F, Ceelen JJM, Sartori R, Nolte H, Nemazanyy I, Pyronnet S, Kruger M, Pende M, Blaauw B. Marabita M, et al. Among authors: pende m. Cell Rep. 2016 Oct 4;17(2):501-513. doi: 10.1016/j.celrep.2016.09.020. Cell Rep. 2016. PMID: 27705797 Free article.
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, Gallazzini M, Olson EN, Lam H, Henske EP, Dong Z, Apte U, Pallet N, Johnson RL, Terzi F, Kwiatkowski DJ, Scoazec JY, Martignoni G, Pende M. Liang N, et al. Among authors: pende m. J Exp Med. 2014 Oct 20;211(11):2249-63. doi: 10.1084/jem.20140341. Epub 2014 Oct 6. J Exp Med. 2014. PMID: 25288394 Free PMC article.
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.
Risson V, Mazelin L, Roceri M, Sanchez H, Moncollin V, Corneloup C, Richard-Bulteau H, Vignaud A, Baas D, Defour A, Freyssenet D, Tanti JF, Le-Marchand-Brustel Y, Ferrier B, Conjard-Duplany A, Romanino K, Bauché S, Hantaï D, Mueller M, Kozma SC, Thomas G, Rüegg MA, Ferry A, Pende M, Bigard X, Koulmann N, Schaeffer L, Gangloff YG. Risson V, et al. Among authors: pende m. J Cell Biol. 2009 Dec 14;187(6):859-74. doi: 10.1083/jcb.200903131. J Cell Biol. 2009. PMID: 20008564 Free PMC article.
Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.
Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M. Rashid T, et al. Among authors: pende m. EMBO J. 2019 Jan 3;38(1):e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12. EMBO J. 2019. PMID: 30420558 Free PMC article.
Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophy.
Mounier R, Lantier L, Leclerc J, Sotiropoulos A, Pende M, Daegelen D, Sakamoto K, Foretz M, Viollet B. Mounier R, et al. Among authors: pende m. FASEB J. 2009 Jul;23(7):2264-73. doi: 10.1096/fj.08-119057. Epub 2009 Feb 23. FASEB J. 2009. PMID: 19237506 Free article.
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