Penetrance of Breast Cancer Susceptibility Genes From the eMERGE III Network.
JNCI Cancer Spectr. 2021.
PMID: 34377931
Free PMC article.
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Penetrance of Breast Cancer Susceptibility Genes From the eMERGE III Network.
Fan X, Wynn J, Shang N, Liu C, Fedotov A, Hallquist MLG, Buchanan AH, Williams MS, Smith ME, Hoell C, Rasmussen-Torvik LJ, Peterson JF, Wiesner GL, Murad AM, Jarvik GP, Gordon AS, Rosenthal EA, Stanaway IB, Crosslin DR, Larson EB, Leppig KA, Henrikson NB, Williams JL, Li R, Hebbring S, Weng C, Shen Y, Crew KD, Chung WK.
Fan X, et al.
JNCI Cancer Spectr. 2021 May 8;5(4):pkab044. doi: 10.1093/jncics/pkab044. eCollection 2021 Aug.
JNCI Cancer Spectr. 2021.
PMID: 34377931
Free PMC article.
METHODS: We studied the penetrance and clinical outcomes of 7 breast cancer susceptibility genes (BRCA1, BRCA2, TP53, CHEK2, ATM, PALB2, and PTEN) in almost 13 458 participants unselected for personal or family history of breast cancer …
METHODS: We studied the penetrance and clinical outcomes of 7 breast cancer susceptibility genes (BRCA1, …
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The Fanconi anaemia/BRCA pathway and cancer susceptibility. Searching for new therapeutic targets.
García MJ, Benítez J.
García MJ, et al.
Clin Transl Oncol. 2008 Feb;10(2):78-84. doi: 10.1007/s12094-008-0160-6.
Clin Transl Oncol. 2008.
PMID: 18258506
Review.
Common and rare low- moderate-penetrance genes, and high-penetrance genes are thought to explain the genetic susceptibility to the disease. Only around 20% of the inherited risk to breast cancer is explained by germline muta …
Common and rare low- moderate-penetrance genes, and high-penetrance genes are thought to explain the genetic …
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