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The following term was not found in PubMed: Pentadecarginine
Page 1
Peptide chemistry toolbox - Transforming natural peptides into peptide therapeutics.
Erak M, Bellmann-Sickert K, Els-Heindl S, Beck-Sickinger AG. Erak M, et al. Bioorg Med Chem. 2018 Jun 1;26(10):2759-2765. doi: 10.1016/j.bmc.2018.01.012. Epub 2018 Jan 31. Bioorg Med Chem. 2018. PMID: 29395804 Review.
The development of solid phase peptide synthesis has released tremendous opportunities for using synthetic peptides in medicinal applications. ...In this mini-review, we present a toolbox of modifications in peptide chemistry for overcoming the main drawbacks …
The development of solid phase peptide synthesis has released tremendous opportunities for using synthetic peptides in medicin …
Peptide siderophores.
Drechsel H, Jung G. Drechsel H, et al. J Pept Sci. 1998 May;4(3):147-81. doi: 10.1002/(SICI)1099-1387(199805)4:3%3C147::AID-PSC136%3E3.0.CO;2-C. J Pept Sci. 1998. PMID: 9643626 Review.
Biosynthesis, transport, regulation and chemical synthesis of natural siderophores and their analogues is of considerable interest for the protein and peptide chemist. This review gives an overview of the structural classes of peptidic siderophores, along with data …
Biosynthesis, transport, regulation and chemical synthesis of natural siderophores and their analogues is of considerable interest for the p …
Peptide diffusion in biomolecular condensates.
Workman RJ, Huang CJ, Lynch GC, Pettitt BM. Workman RJ, et al. Biophys J. 2024 Jun 18;123(12):1668-1675. doi: 10.1016/j.bpj.2024.05.009. Epub 2024 May 15. Biophys J. 2024. PMID: 38751116 Free PMC article.
These solutions readily separate into aqueous and peptide-rich droplet phases. We noted the effect of the peptides being in a solvated, surface, or droplet state on the peptide's diffusion coefficients. Both sequence and peptide conformational d …
These solutions readily separate into aqueous and peptide-rich droplet phases. We noted the effect of the peptides being in a …
Peptide-based coacervates as biomimetic protocells.
Abbas M , Lipiński WP , Wang J , Spruijt E . Abbas M , et al. Chem Soc Rev. 2021 Mar 21;50(6):3690-3705. doi: 10.1039/d0cs00307g. Epub 2021 Feb 22. Chem Soc Rev. 2021. PMID: 33616129 Review.
The main advantage of peptides as building blocks lies in the functional diversity of the amino acid residues, which allows for tailoring of the peptide's phase separation propensity, their selectivity in guest molecule uptake and the physicochemical and cata …
The main advantage of peptides as building blocks lies in the functional diversity of the amino acid residues, which allows for tailo …
Peptide-based covalent inhibitors of protein-protein interactions.
Paulussen FM, Grossmann TN. Paulussen FM, et al. J Pept Sci. 2023 Jan;29(1):e3457. doi: 10.1002/psc.3457. Epub 2022 Nov 9. J Pept Sci. 2023. PMID: 36239115 Free PMC article. Review.
However, certain proteins remain challenging targets when applying inhibitors with a competitive mode of action. For that reason, peptide-based ligands with an irreversible binding mode have gained attention in recent years. This review summarizes examples of covalent inhi …
However, certain proteins remain challenging targets when applying inhibitors with a competitive mode of action. For that reason, peptide …
Mechanisms Inspired Targeting Peptides.
Yuan Y. Yuan Y. Adv Exp Med Biol. 2020;1248:531-546. doi: 10.1007/978-981-15-3266-5_21. Adv Exp Med Biol. 2020. PMID: 32185724 Review.
Peptides, as a large group of molecules, are composed of amino acid residues and can be divided into linear or cyclic peptides according to the structure. Over 13,000 molecules of natural peptides have been found and many of them have been well studied. In ar …
Peptides, as a large group of molecules, are composed of amino acid residues and can be divided into linear or cyclic peptides …
Peptide retention time prediction.
Moruz L, Käll L. Moruz L, et al. Mass Spectrom Rev. 2017 Sep;36(5):615-623. doi: 10.1002/mas.21488. Epub 2016 Jan 22. Mass Spectrom Rev. 2017. PMID: 26799864 Review.
Most methods for interpreting data from shotgun proteomics experiments are to large degree dependent on being able to predict properties of peptide-ions. Often such predicted properties are limited to molecular mass and fragment spectra, but here we put focus on a perhaps …
Most methods for interpreting data from shotgun proteomics experiments are to large degree dependent on being able to predict properties of …
Mimetics of the peptide beta-strand.
Glenn MP, Fairlie DP. Glenn MP, et al. Mini Rev Med Chem. 2002 Oct;2(5):433-45. doi: 10.2174/1389557023405747. Mini Rev Med Chem. 2002. PMID: 12370045 Review.
Bioactive structures of peptides represent important clues for drug discovery and development although peptides themselves have substantial limitations as drugs. One promising approach to overcoming the limitations of peptides is to progressively replace amid …
Bioactive structures of peptides represent important clues for drug discovery and development although peptides themselves hav …
Designed Peptide Assemblies for Efficient Gene Delivery.
Ma H, Cao M. Ma H, et al. Langmuir. 2022 Nov 15;38(45):13627-13634. doi: 10.1021/acs.langmuir.2c02197. Epub 2022 Nov 1. Langmuir. 2022. PMID: 36318179 Review.
By having these merits, peptidic gene vectors are developing fast, showing outstanding advantages compared to liposome and polymer vectors. ...The new arising research area of peptide-based artificial viruses for gene and ribonucleoprotein delivery has also been rev …
By having these merits, peptidic gene vectors are developing fast, showing outstanding advantages compared to liposome and polymer ve …
Targeting Tumors Using Peptides.
Scodeller P, Asciutto EK. Scodeller P, et al. Molecules. 2020 Feb 13;25(4):808. doi: 10.3390/molecules25040808. Molecules. 2020. PMID: 32069856 Free PMC article. Review.
Because of the dense stroma and high interstitial fluid pressure of solid tumors, the penetration of higher Mw compounds is unfavored and being small thus becomes an advantage. This review covers a wide range of peptidic ligands-linear, cyclic, macrocyclic and cyclotidic …
Because of the dense stroma and high interstitial fluid pressure of solid tumors, the penetration of higher Mw compounds is unfavored and be …
3,339,523 results
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