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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
1945 2
1946 6
1947 7
1948 15
1949 3
1950 11
1951 19
1952 15
1953 11
1954 9
1955 5
1956 6
1957 10
1958 7
1959 4
1960 5
1961 2
1962 2
1963 2
1964 3
1966 5
1967 2
1968 5
1969 5
1970 6
1971 2
1972 3
1973 2
1974 4
1975 15
1976 27
1977 21
1978 20
1979 14
1980 14
1981 10
1982 22
1983 25
1984 44
1985 41
1986 27
1987 45
1988 74
1989 128
1990 154
1991 206
1992 155
1993 143
1994 127
1995 100
1996 96
1997 81
1998 71
1999 42
2000 42
2001 49
2002 48
2003 45
2004 48
2005 40
2006 62
2007 63
2008 60
2009 78
2010 64
2011 60
2012 58
2013 60
2014 59
2015 63
2016 56
2017 53
2018 65
2019 70
2020 58
2021 42
2022 47
2023 47
2024 20

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3,112 results

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Page 1
Pentamidine: a review.
Sands M, Kron MA, Brown RB. Sands M, et al. Rev Infect Dis. 1985 Sep-Oct;7(5):625-34. doi: 10.1093/clinids/7.5.625. Rev Infect Dis. 1985. PMID: 3903942 Review.
However, pentamidine appears to kill nonreplicating P. carinii. The mechanism of killing is unexplained. The pharmacokinetics of pentamidine has been incompletely studied in humans. The estimated volume of distribution is 3 liters/kg. ...
However, pentamidine appears to kill nonreplicating P. carinii. The mechanism of killing is unexplained. The pharmacokinetics of p …
Repurposing pentamidine for cancer immunotherapy by targeting the PD1/PD-L1 immune checkpoint.
Gu T, Tian X, Wang Y, Yang W, Li W, Song M, Zhao R, Wang M, Gao Q, Li T, Zhang C, Kundu JK, Liu K, Dong Z, Lee MH. Gu T, et al. Front Immunol. 2023 May 2;14:1145028. doi: 10.3389/fimmu.2023.1145028. eCollection 2023. Front Immunol. 2023. PMID: 37205112 Free PMC article.
Pentamidine promoted T-cell activation by blocking the PD-1/PD-L1 interaction. In vivo administration of pentamidine attenuated the tumor growth and prolonged the survival of tumor-bearing mice in PD-L1 humanized murine tumor cell allograft models. ...
Pentamidine promoted T-cell activation by blocking the PD-1/PD-L1 interaction. In vivo administration of pentamidine attenuate …
Ninety Years of Pentamidine: The Development and Applications of Pentamidine and its Analogs.
Zhang B, Jin Y, Zhang L, Wang H, Wang X. Zhang B, et al. Curr Med Chem. 2022;29(26):4602-4609. doi: 10.2174/0929867329666220314121446. Curr Med Chem. 2022. PMID: 35289252 Review.
Pentamidine, an FDA-approved human drug for many protozoal infections, was initially synthesized in the late 1930s and first reported to be curative for parasitosis in the 1940s. ...This mini-review highlights the development and applications of pentamidine and its …
Pentamidine, an FDA-approved human drug for many protozoal infections, was initially synthesized in the late 1930s and first reported …
Pentamidine: a review.
Wispelwey B, Pearson RD. Wispelwey B, et al. Infect Control Hosp Epidemiol. 1991 Jun;12(6):375-82. doi: 10.1086/646360. Infect Control Hosp Epidemiol. 1991. PMID: 2071882 Review. No abstract available.
Pneumocystis carinii pneumonia.
Thomas S, O'Doherty M, Bateman N. Thomas S, et al. BMJ. 1990 Jan 27;300(6719):211-2. doi: 10.1136/bmj.300.6719.211. BMJ. 1990. PMID: 2106927 Free PMC article. Review. No abstract available.
Pentamidine. A risk-benefit analysis.
Wispelwey B, Pearson R. Wispelwey B, et al. Drug Saf. 1990 May-Jun;5(3):212-9. doi: 10.2165/00002018-199005030-00006. Drug Saf. 1990. PMID: 2190597 Review.
With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has greatly increased. This review summarises its pharmacology, its toxicity and clinical experience in the treatment of Pneumocystis carinii pneumonia ( …
With the advent of the acquired immunodeficiency syndrome (AIDS), the therapeutic importance of pentamidine isethionate has greatly i …
New pentamidine analogues in medicinal chemistry.
Porcheddu A, Giacomelli G, De Luca L. Porcheddu A, et al. Curr Med Chem. 2012;19(34):5819-36. doi: 10.2174/092986712804143268. Curr Med Chem. 2012. PMID: 23092128 Review.
Sixty years after its introduction, 1,5-bis(4-amidinophenoxy)pentane (Pentamidine) is still one of the most used drugs for the treatment of the first stage of Human African trypanosomiasis and other neglected diseases such as malaria and leishmaniasis. ...A great effort ha …
Sixty years after its introduction, 1,5-bis(4-amidinophenoxy)pentane (Pentamidine) is still one of the most used drugs for the treatm …
A Systematic Review of Drug-Carrying Nanosystems Used in the Treatment of Leishmaniasis.
Registre C, Soares RDOA, Rubio KTS, Santos ODH, Carneiro SP. Registre C, et al. ACS Infect Dis. 2023 Mar 10;9(3):423-449. doi: 10.1021/acsinfecdis.2c00632. Epub 2023 Feb 16. ACS Infect Dis. 2023. PMID: 36795604 Review.
Chemotherapy consists of the use of pentavalent antimonial, amphotericin B, pentamidine, miltefosine, and paromomycin. However, these drugs are associated with some drawbacks such as high toxicity, administration by parenteral route, and most seriously the resistance of so …
Chemotherapy consists of the use of pentavalent antimonial, amphotericin B, pentamidine, miltefosine, and paromomycin. However, these …
Aerosolised pentamidine.
O'Doherty MJ, Thomas SH, Nunan TO, Bateman NT. O'Doherty MJ, et al. Lancet. 1989 Mar 4;1(8636):501-2. doi: 10.1016/s0140-6736(89)91404-9. Lancet. 1989. PMID: 2563874 No abstract available.
Pneumocystis pneumonia.
Neibart EP. Neibart EP. Ann Intern Med. 1988 Mar;108(3):489-90. doi: 10.7326/0003-4819-108-3-489_2. Ann Intern Med. 1988. PMID: 3257673 No abstract available.
3,112 results