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Modulation of myoblast fusion by caveolin-3 in dystrophic skeletal muscle cells: implications for Duchenne muscular dystrophy and limb-girdle muscular dystrophy-1C.
Volonte D, Peoples AJ, Galbiati F. Volonte D, et al. Among authors: peoples aj. Mol Biol Cell. 2003 Oct;14(10):4075-88. doi: 10.1091/mbc.e03-03-0161. Epub 2003 Aug 7. Mol Biol Cell. 2003. PMID: 14517320 Free PMC article.
Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2.
Gavrish E, Sit CS, Cao S, Kandror O, Spoering A, Peoples A, Ling L, Fetterman A, Hughes D, Bissell A, Torrey H, Akopian T, Mueller A, Epstein S, Goldberg A, Clardy J, Lewis K. Gavrish E, et al. Chem Biol. 2014 Apr 24;21(4):509-518. doi: 10.1016/j.chembiol.2014.01.014. Epub 2014 Mar 27. Chem Biol. 2014. PMID: 24684906 Free PMC article.
A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K. Ling LL, et al. Among authors: peoples aj. Nature. 2015 Jan 22;517(7535):455-9. doi: 10.1038/nature14098. Epub 2015 Jan 7. Nature. 2015. PMID: 25561178 Free PMC article.
Neocitreamicins I and II, novel antibiotics with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci.
Peoples AJ, Zhang Q, Millett WP, Rothfeder MT, Pescatore BC, Madden AA, Ling LL, Moore CM. Peoples AJ, et al. J Antibiot (Tokyo). 2008 Jul;61(7):457-63. doi: 10.1038/ja.2008.62. J Antibiot (Tokyo). 2008. PMID: 18776658 Free PMC article.
Erratum: A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K. Ling LL, et al. Among authors: peoples aj. Nature. 2015 Apr 16;520(7547):388. doi: 10.1038/nature14303. Epub 2015 Feb 25. Nature. 2015. PMID: 25731174 No abstract available.
Reducing the Bottleneck in Discovery of Novel Antibiotics.
Jones MB, Nierman WC, Shan Y, Frank BC, Spoering A, Ling L, Peoples A, Zullo A, Lewis K, Nelson KE. Jones MB, et al. Microb Ecol. 2017 Apr;73(3):658-667. doi: 10.1007/s00248-016-0889-3. Epub 2016 Nov 28. Microb Ecol. 2017. PMID: 27896376
Isofuranonaphthoquinone produced by an Actinoplanes isolate.
Zhang Q, Peoples AJ, Rothfeder MT, Millett WP, Pescatore BC, Ling LL, Moore CM. Zhang Q, et al. Among authors: peoples aj. J Nat Prod. 2009 Jun;72(6):1213-5. doi: 10.1021/np8005716. J Nat Prod. 2009. PMID: 19449881 Free PMC article.
Structural studies suggest aggregation as one of the modes of action for teixobactin.
Öster C, Walkowiak GP, Hughes DE, Spoering AL, Peoples AJ, Catherwood AC, Tod JA, Lloyd AJ, Herrmann T, Lewis K, Dowson CG, Lewandowski JR. Öster C, et al. Among authors: peoples aj. Chem Sci. 2018 Sep 20;9(47):8850-8859. doi: 10.1039/c8sc03655a. eCollection 2018 Dec 21. Chem Sci. 2018. PMID: 30627403 Free PMC article.
Diacid linkers that promote parallel beta-sheet secondary structure in water.
Freire F, Fisk JD, Peoples AJ, Ivancic M, Guzei IA, Gellman SH. Freire F, et al. Among authors: peoples aj. J Am Chem Soc. 2008 Jun 25;130(25):7839-41. doi: 10.1021/ja802042c. Epub 2008 May 29. J Am Chem Soc. 2008. PMID: 18507461 Free PMC article.
Thermodynamic analysis of beta-sheet secondary structure by backbone thioester exchange.
Hadley EB, Witek AM, Freire F, Peoples AJ, Gellman SH. Hadley EB, et al. Among authors: peoples aj. Angew Chem Int Ed Engl. 2007;46(37):7056-9. doi: 10.1002/anie.200702449. Angew Chem Int Ed Engl. 2007. PMID: 17691093 No abstract available.
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