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GABA(A) receptors as molecular sites of ethanol action. Direct or indirect actions?
Aguayo LG, Peoples RW, Yeh HH, Yevenes GE. Aguayo LG, et al. Among authors: peoples rw. Curr Top Med Chem. 2002 Aug;2(8):869-85. doi: 10.2174/1568026023393426. Curr Top Med Chem. 2002. PMID: 12171577 Review.
Role of membrane GM1 on early neuronal membrane actions of Aβ during onset of Alzheimer's disease.
Fernández-Pérez EJ, Sepúlveda FJ, Peoples R, Aguayo LG. Fernández-Pérez EJ, et al. Biochim Biophys Acta Mol Basis Dis. 2017 Dec;1863(12):3105-3116. doi: 10.1016/j.bbadis.2017.08.013. Epub 2017 Aug 24. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28844949
The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation.
Peters C, Sepúlveda FJ, Fernández-Pérez EJ, Peoples RW, Aguayo LG. Peters C, et al. Among authors: peoples rw. J Alzheimers Dis. 2016 May 6;53(1):197-207. doi: 10.3233/JAD-160170. J Alzheimers Dis. 2016. PMID: 27163827
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease.
Sepúlveda FJ, Fierro H, Fernandez E, Castillo C, Peoples RW, Opazo C, Aguayo LG. Sepúlveda FJ, et al. Among authors: peoples rw. Neurobiol Aging. 2014 Mar;35(3):472-81. doi: 10.1016/j.neurobiolaging.2013.08.035. Epub 2013 Oct 8. Neurobiol Aging. 2014. PMID: 24112789
A Single phenylalanine residue in the main intracellular loop of α1 γ-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol.
Moraga-Cid G, Yevenes GE, Schmalzing G, Peoples RW, Aguayo LG. Moraga-Cid G, et al. Among authors: peoples rw. Anesthesiology. 2011 Sep;115(3):464-73. doi: 10.1097/ALN.0b013e31822550f7. Anesthesiology. 2011. PMID: 21673564 Free PMC article.
Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property.
Sepulveda FJ, Parodi J, Peoples RW, Opazo C, Aguayo LG. Sepulveda FJ, et al. Among authors: peoples rw. PLoS One. 2010 Jul 27;5(7):e11820. doi: 10.1371/journal.pone.0011820. PLoS One. 2010. PMID: 20676404 Free PMC article.
Molecular requirements for ethanol differential allosteric modulation of glycine receptors based on selective Gbetagamma modulation.
Yevenes GE, Moraga-Cid G, Avila A, Guzmán L, Figueroa M, Peoples RW, Aguayo LG. Yevenes GE, et al. Among authors: peoples rw. J Biol Chem. 2010 Sep 24;285(39):30203-13. doi: 10.1074/jbc.M110.134676. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20647311 Free PMC article.
A selective G betagamma-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol.
Yevenes GE, Moraga-Cid G, Peoples RW, Schmalzing G, Aguayo LG. Yevenes GE, et al. Among authors: peoples rw. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20523-8. doi: 10.1073/pnas.0806257105. Epub 2008 Dec 12. Proc Natl Acad Sci U S A. 2008. PMID: 19074265 Free PMC article.
Modulation of glycine-activated ion channel function by G-protein betagamma subunits.
Yevenes GE, Peoples RW, Tapia JC, Parodi J, Soto X, Olate J, Aguayo LG. Yevenes GE, et al. Among authors: peoples rw. Nat Neurosci. 2003 Aug;6(8):819-24. doi: 10.1038/nn1095. Nat Neurosci. 2003. PMID: 12858180
Interactions among positions in the third and fourth membrane-associated domains at the intersubunit interface of the N-methyl-D-aspartate receptor forming sites of alcohol action.
Ren H, Zhao Y, Dwyer DS, Peoples RW. Ren H, et al. Among authors: peoples rw. J Biol Chem. 2012 Aug 10;287(33):27302-12. doi: 10.1074/jbc.M111.338921. Epub 2012 Jun 19. J Biol Chem. 2012. PMID: 22715100 Free PMC article.
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