Pepers BA - Search Results

1

Effect of post-mortem delay on N-terminal huntingtin protein fragments in human control and Huntington disease brain lysates.

Schut MH, Patassini S, Kim EH, Bullock J, Waldvogel HJ, Faull RLM, Pepers BA, den Dunnen JT, van Ommen GB, van Roon-Mom WMC. Schut MH, et al. Among authors: pepers ba. PLoS One. 2017 Jun 1;12(6):e0178556. doi: 10.1371/journal.pone.0178556. eCollection 2017. PLoS One. 2017. PMID: 28570578 Free PMC article.

2

Strong aggregation and increased toxicity of polyleucine over polyglutamine stretches in mammalian cells.

Dorsman JC, Pepers B, Langenberg D, Kerkdijk H, Ijszenga M, den Dunnen JT, Roos RA, van Ommen GJ. Dorsman JC, et al. Hum Mol Genet. 2002 Jun 15;11(13):1487-96. doi: 10.1093/hmg/11.13.1487. Hum Mol Genet. 2002. PMID: 12045202

3

Interruption of perfect CAG repeats by CAA triplets improves the stability of glutamine-encoding repeat sequences.

Dorsman JC, Bremmer-Bout M, Pepers B, van Ommen GJ, Den Dunnen JT. Dorsman JC, et al. Biotechniques. 2002 Nov;33(5):976-8. doi: 10.2144/02335bm01. Biotechniques. 2002. PMID: 12449369 Free article. No abstract available.

4

Epitope mapping of monoclonal antibody 4C8 recognizing the protein huntingtin.

Cong SY, Pepers BA, Roos RA, Van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Hybridoma (Larchmt). 2005 Oct;24(5):231-5. doi: 10.1089/hyb.2005.24.231. Hybridoma (Larchmt). 2005. PMID: 16225422

5

Small N-terminal mutant huntingtin fragments, but not wild type, are mainly present in monomeric form: Implications for pathogenesis.

Cong SY, Pepers BA, Roos RA, van Ommen GJ, Dorsman JC. Cong SY, et al. Among authors: pepers ba. Exp Neurol. 2006 Jun;199(2):257-64. doi: 10.1016/j.expneurol.2005.11.008. Epub 2005 Dec 27. Exp Neurol. 2006. PMID: 16380118

6

Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease.

van Roon-Mom WM, Pepers BA, 't Hoen PA, Verwijmeren CA, den Dunnen JT, Dorsman JC, van Ommen GB. van Roon-Mom WM, et al. Among authors: pepers ba. BMC Mol Biol. 2008 Oct 9;9:84. doi: 10.1186/1471-2199-9-84. BMC Mol Biol. 2008. PMID: 18844975 Free PMC article.

7

Cost-effective HRMA pre-sequence typing of clone libraries; application to phage display selection.

Pepers BA, Schut MH, Vossen RH, van Ommen GJ, den Dunnen JT, van Roon-Mom WM. Pepers BA, et al. BMC Biotechnol. 2009 May 22;9:50. doi: 10.1186/1472-6750-9-50. BMC Biotechnol. 2009. PMID: 19463169 Free PMC article.

8

Targeting several CAG expansion diseases by a single antisense oligonucleotide.

Evers MM, Pepers BA, van Deutekom JC, Mulders SA, den Dunnen JT, Aartsma-Rus A, van Ommen GJ, van Roon-Mom WM. Evers MM, et al. Among authors: pepers ba. PLoS One. 2011;6(9):e24308. doi: 10.1371/journal.pone.0024308. Epub 2011 Sep 1. PLoS One. 2011. PMID: 21909428 Free PMC article.

9

Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: removal of the CAG containing exon.

Evers MM, Tran HD, Zalachoras I, Pepers BA, Meijer OC, den Dunnen JT, van Ommen GJ, Aartsma-Rus A, van Roon-Mom WM. Evers MM, et al. Among authors: pepers ba. Neurobiol Dis. 2013 Oct;58:49-56. doi: 10.1016/j.nbd.2013.04.019. Epub 2013 May 6. Neurobiol Dis. 2013. PMID: 23659897 Free article.

10

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis.

Bomer N, den Hollander W, Ramos YF, Bos SD, van der Breggen R, Lakenberg N, Pepers BA, van Eeden AE, Darvishan A, Tobi EW, Duijnisveld BJ, van den Akker EB, Heijmans BT, van Roon-Mom WM, Verbeek FJ, van Osch GJ, Nelissen RG, Slagboom PE, Meulenbelt I. Bomer N, et al. Among authors: pepers ba. Ann Rheum Dis. 2015 Aug;74(8):1571-9. doi: 10.1136/annrheumdis-2013-204739. Epub 2014 Apr 2. Ann Rheum Dis. 2015. PMID: 24695009 Free PMC article.

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