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Recent developments in adeno-associated virus vector technology.
Büning H, Perabo L, Coutelle O, Quadt-Humme S, Hallek M. Büning H, et al. Among authors: perabo l. J Gene Med. 2008 Jul;10(7):717-33. doi: 10.1002/jgm.1205. J Gene Med. 2008. PMID: 18452237 Review.
Successful target cell transduction of capsid-engineered rAAV vectors requires clathrin-dependent endocytosis.
Uhrig S, Coutelle O, Wiehe T, Perabo L, Hallek M, Büning H. Uhrig S, et al. Among authors: perabo l. Gene Ther. 2012 Feb;19(2):210-8. doi: 10.1038/gt.2011.78. Epub 2011 Jun 9. Gene Ther. 2012. PMID: 21654820 Free article.
A novel directed evolution method to enhance cell-type specificity of adeno-associated virus vectors.
Märsch S, Huber A, Hallek M, Büning H, Perabo L. Märsch S, et al. Among authors: perabo l. Comb Chem High Throughput Screen. 2010 Nov;13(9):807-12. doi: 10.2174/138620710792927385. Comb Chem High Throughput Screen. 2010. PMID: 20615200
Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions.
White K, Büning H, Kritz A, Janicki H, McVey J, Perabo L, Murphy G, Odenthal M, Work LM, Hallek M, Nicklin SA, Baker AH. White K, et al. Among authors: perabo l. Gene Ther. 2008 Mar;15(6):443-51. doi: 10.1038/sj.gt.3303077. Epub 2007 Nov 15. Gene Ther. 2008. PMID: 18004401 Free article.
Receptor targeting of adeno-associated virus vectors.
Büning H, Ried MU, Perabo L, Gerner FM, Huttner NA, Enssle J, Hallek M. Büning H, et al. Among authors: perabo l. Gene Ther. 2003 Jul;10(14):1142-51. doi: 10.1038/sj.gt.3301976. Gene Ther. 2003. PMID: 12833123 Review.
Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies.
Huttner NA, Girod A, Perabo L, Edbauer D, Kleinschmidt JA, Büning H, Hallek M. Huttner NA, et al. Among authors: perabo l. Gene Ther. 2003 Dec;10(26):2139-47. doi: 10.1038/sj.gt.3302123. Gene Ther. 2003. PMID: 14625569
Engineering adeno-associated virus serotype 2-based targeting vectors using a new insertion site-position 453-and single point mutations.
Boucas J, Lux K, Huber A, Schievenbusch S, von Freyend MJ, Perabo L, Quadt-Humme S, Odenthal M, Hallek M, Büning H. Boucas J, et al. Among authors: perabo l. J Gene Med. 2009 Dec;11(12):1103-13. doi: 10.1002/jgm.1392. J Gene Med. 2009. PMID: 19777441
Gene transfer into human cord blood-derived CD34(+) cells by adeno-associated viral vectors.
Schuhmann NK, Pozzoli O, Sallach J, Huber A, Avitabile D, Perabo L, Rappl G, Capogrossi MC, Hallek M, Pesce M, Büning H. Schuhmann NK, et al. Among authors: perabo l. Exp Hematol. 2010 Sep;38(9):707-17. doi: 10.1016/j.exphem.2010.04.016. Epub 2010 May 4. Exp Hematol. 2010. PMID: 20447441
Optimization of stealth adeno-associated virus vectors by randomization of immunogenic epitopes.
Maersch S, Huber A, Büning H, Hallek M, Perabo L. Maersch S, et al. Among authors: perabo l. Virology. 2010 Feb 5;397(1):167-75. doi: 10.1016/j.virol.2009.10.021. Epub 2009 Nov 18. Virology. 2010. PMID: 19926109 Free article.
Efficient gene transfer to periodontal ligament cells and human gingival fibroblasts by adeno-associated virus vectors.
Kunze M, Huber A, Krajewski A, Lowden E, Schuhmann N, Buening H, Hallek M, Noack M, Perabo L. Kunze M, et al. Among authors: perabo l. J Dent. 2009 Jul;37(7):502-8. doi: 10.1016/j.jdent.2009.03.001. Epub 2009 Apr 11. J Dent. 2009. PMID: 19362764
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