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Microtubule-disrupting effects of gallium chloride in vitro.
Perchellet EM, Ladesich JB, Collery P, Perchellet JP. Perchellet EM, et al. Anticancer Drugs. 1999 Jun;10(5):477-88. doi: 10.1097/00001813-199906000-00008. Anticancer Drugs. 1999. PMID: 10477168
Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.
Wang Y, Perchellet EM, Ward MM, Lou K, Hua DH, Perchellet JP. Wang Y, et al. Anticancer Drugs. 2005 Oct;16(9):953-67. doi: 10.1097/01.cad.0000180123.24031.5a. Anticancer Drugs. 2005. PMID: 16162972
Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro.
Perchellet JP, Perchellet EM, Singh CR, Monnett MT, Studer ER, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Buszek KR. Perchellet JP, et al. Among authors: perchellet em. Anticancer Res. 2014 Apr;34(4):1643-55. Anticancer Res. 2014. PMID: 24692693 Free PMC article.
Antitumor effects of synthetic 6,7-annulated-4-substituted indole compounds in L1210 leukemic cells in vitro.
Perchellet JP, Waters AM, Perchellet EM, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Chandrasoma N, Buszek KR. Perchellet JP, et al. Among authors: perchellet em. Anticancer Res. 2012 Nov;32(11):4671-84. Anticancer Res. 2012. PMID: 23155229 Free PMC article.
Bioactivity of synthetic 2-halo-3-aryl-4(3H)-quinazoliniminium halides in L1210 leukemia and SK-BR-3 mammary tumor cells in vitro.
Perchellet JP, Waters AM, Perchellet EM, Naganaboina VK, Chandra KL, Desper J, Rayat S. Perchellet JP, et al. Among authors: perchellet em. Anticancer Res. 2011 Jun;31(6):2083-93. Anticancer Res. 2011. PMID: 21737626
Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins.
Perchellet JP, Perchellet EM, Crow KR, Buszek KR, Brown N, Ellappan S, Gao G, Luo D, Minatoya M, Lushington GH. Perchellet JP, et al. Among authors: perchellet em. Int J Mol Med. 2009 Nov;24(5):633-43. doi: 10.3892/ijmm_00000274. Int J Mol Med. 2009. PMID: 19787197 Free PMC article.
Synthesis, molecular targets, and antitumor activities of substituted tetrahydro-1-oxopyrano[4,3-b][1]benzopyrans and nanogels for drug delivery.
Perchellet EM, Perchellet JP, Ganta CK, Troyer DL, Shi A, Hua DH. Perchellet EM, et al. Anticancer Agents Med Chem. 2009 Oct;9(8):864-76. doi: 10.2174/187152009789124682. Anticancer Agents Med Chem. 2009. PMID: 19538164 Review.
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