Perchellet JP - Search Results

1

Induction of poly(ADP-ribose) polymerase-1 cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines.

Wang Y, Perchellet EM, Tamura M, Hua DH, Perchellet JP. Wang Y, et al. Among authors: perchellet jp, perchellet em. Cancer Lett. 2002 Dec 15;188(1-2):73-83. doi: 10.1016/s0304-3835(02)00493-7. Cancer Lett. 2002. PMID: 12406551

2

Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro.

Perchellet EM, Sperfslage BJ, Wang Y, Huang X, Tamura M, Hua DH, Perchellet JP. Perchellet EM, et al. Among authors: perchellet jp. Anticancer Drugs. 2002 Jul;13(6):567-81. doi: 10.1097/00001813-200207000-00003. Anticancer Drugs. 2002. PMID: 12172502

3

Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.

Perchellet EM, Wang Y, Weber RL, Sperfslage BJ, Lou K, Crossland J, Hua DH, Perchellet JP. Perchellet EM, et al. Among authors: perchellet jp. Biochem Pharmacol. 2004 Feb 1;67(3):523-37. doi: 10.1016/j.bcp.2003.09.012. Biochem Pharmacol. 2004. PMID: 15037204

4

Syntheses and bioactivities of substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetrones. Unusual reactivities with amines.

Hua DH, Tamura M, Huang X, Stephany HA, Helfrich BA, Perchellet EM, Sperfslage BJ, Perchellet JP, Jiang S, Kyle DE, Chiang PK. Hua DH, et al. Among authors: perchellet jp, perchellet em. J Org Chem. 2002 May 3;67(9):2907-12. doi: 10.1021/jo010958s. J Org Chem. 2002. PMID: 11975545

5

Imidazole-4,5-dicarboxamide derivatives with antiproliferative activity against HL-60 cells.

Perchellet EM, Perchellet JP, Baures PW. Perchellet EM, et al. Among authors: perchellet jp. J Med Chem. 2005 Sep 22;48(19):5955-65. doi: 10.1021/jm050160r. J Med Chem. 2005. PMID: 16161999

6

Total syntheses of (+)-chloropuupehenone and (+)-chloropuupehenol and their analogues and evaluation of their bioactivities.

Hua DH, Huang X, Chen Y, Battina SK, Tamura M, Noh SK, Koo SI, Namatame I, Tomoda H, Perchellet EM, Perchellet JP. Hua DH, et al. Among authors: perchellet jp, perchellet em. J Org Chem. 2004 Sep 3;69(18):6065-78. doi: 10.1021/jo0491399. J Org Chem. 2004. PMID: 15373492

7

Preparation and cytotoxic activity of some new rhodomycin derivatives bearing modifications in the sugar moiety.

Algiannis N, Pouli N, Marakos P, Skaltsounis AL, Florent JC, Perchellet EM, Sperfslage BJ, McIlvain CJ, Perchellet JP. Algiannis N, et al. Among authors: perchellet jp, perchellet em. J Antibiot (Tokyo). 2002 Feb;55(2):181-90. doi: 10.7164/antibiotics.55.181. J Antibiot (Tokyo). 2002. PMID: 12003000 Free article.

8

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.

Kozel C, Thompson B, Hustak S, Moore C, Nakashima A, Singh CR, Reid M, Cox C, Papadopoulos E, Luna RE, Anderson A, Tagami H, Hiraishi H, Slone EA, Yoshino KI, Asano M, Gillaspie S, Nietfeld J, Perchellet JP, Rothenburg S, Masai H, Wagner G, Beeser A, Kikkawa U, Fleming SD, Asano K. Kozel C, et al. Among authors: perchellet jp. Nucleic Acids Res. 2016 Oct 14;44(18):8704-8713. doi: 10.1093/nar/gkw559. Epub 2016 Jun 20. Nucleic Acids Res. 2016. PMID: 27325740 Free PMC article.

9

Mechanisms by which synthetic 6,7-annulated-4-substituted indole compounds with anti-proliferative activity disrupt mitosis and block cytokinesis in human HL-60 tumor cells in vitro.

Perchellet JP, Perchellet EM, Singh CR, Monnett MT, Studer ER, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Buszek KR. Perchellet JP, et al. Anticancer Res. 2014 Apr;34(4):1643-55. Anticancer Res. 2014. PMID: 24692693 Free PMC article.

10

Antitumor effects of synthetic 6,7-annulated-4-substituted indole compounds in L1210 leukemic cells in vitro.

Perchellet JP, Waters AM, Perchellet EM, Thornton PD, Brown N, Hill D, Neuenswander B, Lushington GH, Santini C, Chandrasoma N, Buszek KR. Perchellet JP, et al. Anticancer Res. 2012 Nov;32(11):4671-84. Anticancer Res. 2012. PMID: 23155229 Free PMC article.

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