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Genetic deficiency of p38alpha reveals its critical role in myoblast cell cycle exit: the p38alpha-JNK connection.
Perdiguero E, Ruiz-Bonilla V, Serrano AL, Muñoz-Cánoves P. Perdiguero E, et al. Cell Cycle. 2007 Jun 1;6(11):1298-303. doi: 10.4161/cc.6.11.4315. Epub 2007 Jun 20. Cell Cycle. 2007. PMID: 17534150 Review.
Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals.
Segalés J, Perdiguero E, Serrano AL, Sousa-Victor P, Ortet L, Jardí M, Budanov AV, Garcia-Prat L, Sandri M, Thomson DM, Karin M, Hee Lee J, Muñoz-Cánoves P. Segalés J, et al. Among authors: perdiguero e. Nat Commun. 2020 Jan 13;11(1):189. doi: 10.1038/s41467-019-13832-9. Nat Commun. 2020. PMID: 31929511 Free PMC article.
Regulation of Cdc25C activity during the meiotic G2/M transition.
Perdiguero E, Nebreda AR. Perdiguero E, et al. Cell Cycle. 2004 Jun;3(6):733-7. Epub 2004 Jun 8. Cell Cycle. 2004. PMID: 15136768 Review.
Regulation of skeletal muscle gene expression by p38 MAP kinases.
Lluís F, Perdiguero E, Nebreda AR, Muñoz-Cánoves P. Lluís F, et al. Among authors: perdiguero e. Trends Cell Biol. 2006 Jan;16(1):36-44. doi: 10.1016/j.tcb.2005.11.002. Epub 2005 Dec 1. Trends Cell Biol. 2006. PMID: 16325404 Review.
Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.
Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardí M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Muñoz-Cánoves P. Perdiguero E, et al. EMBO J. 2007 Mar 7;26(5):1245-56. doi: 10.1038/sj.emboj.7601587. Epub 2007 Feb 15. EMBO J. 2007. PMID: 17304211 Free PMC article.
p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation.
Ventura JJ, Tenbaum S, Perdiguero E, Huth M, Guerra C, Barbacid M, Pasparakis M, Nebreda AR. Ventura JJ, et al. Among authors: perdiguero e. Nat Genet. 2007 Jun;39(6):750-8. doi: 10.1038/ng2037. Epub 2007 Apr 29. Nat Genet. 2007. PMID: 17468755
Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy.
Serrano AL, Baeza-Raja B, Perdiguero E, Jardí M, Muñoz-Cánoves P. Serrano AL, et al. Among authors: perdiguero e. Cell Metab. 2008 Jan;7(1):33-44. doi: 10.1016/j.cmet.2007.11.011. Cell Metab. 2008. PMID: 18177723
Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases.
Ruiz-Bonilla V, Perdiguero E, Gresh L, Serrano AL, Zamora M, Sousa-Victor P, Jardí M, Wagner EF, Muñoz-Cánoves P. Ruiz-Bonilla V, et al. Among authors: perdiguero e. Cell Cycle. 2008 Jul 15;7(14):2208-14. doi: 10.4161/cc.7.14.6273. Epub 2008 May 12. Cell Cycle. 2008. PMID: 18641461
p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure.
Heinrichsdorff J, Luedde T, Perdiguero E, Nebreda AR, Pasparakis M. Heinrichsdorff J, et al. Among authors: perdiguero e. EMBO Rep. 2008 Oct;9(10):1048-54. doi: 10.1038/embor.2008.149. Epub 2008 Aug 15. EMBO Rep. 2008. PMID: 18704119 Free PMC article.
Epigenetic regulation of myogenesis.
Perdiguero E, Sousa-Victor P, Ballestar E, Muñoz-Cánoves P. Perdiguero E, et al. Epigenetics. 2009 Nov 16;4(8):541-50. doi: 10.4161/epi.4.8.10258. Epub 2009 Nov 5. Epigenetics. 2009. PMID: 20009536 Review.
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