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Arg encodes a widely expressed 145 kDa protein-tyrosine kinase.
Perego R, Ron D, Kruh GD. Perego R, et al. Oncogene. 1991 Oct;6(10):1899-902. Oncogene. 1991. PMID: 1923513
Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a.
Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Schiering N, et al. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. doi: 10.1073/pnas.1734128100. Epub 2003 Oct 14. Proc Natl Acad Sci U S A. 2003. PMID: 14559966 Free PMC article.
Regulation of the wild-type and Y1235D mutant Met kinase activation.
Cristiani C, Rusconi L, Perego R, Schiering N, Kalisz HM, Knapp S, Isacchi A. Cristiani C, et al. Biochemistry. 2005 Nov 1;44(43):14110-9. doi: 10.1021/bi051242k. Biochemistry. 2005. PMID: 16245927
Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.
Visco C, Magistrelli G, Bosotti R, Perego R, Rusconi L, Toma S, Zamai M, Acuto O, Isacchi A. Visco C, et al. Biochemistry. 2000 Mar 14;39(10):2784-91. doi: 10.1021/bi991840x. Biochemistry. 2000. PMID: 10704231
Role of the Src homology 2 domains and interdomain regions in ZAP-70 phosphorylation and enzymatic activity.
Magistrelli G, Bosotti R, Valsasina B, Visco C, Perego R, Toma S, Acuto O, Isacchi A. Magistrelli G, et al. Eur J Biochem. 1999 Dec;266(3):1166-73. doi: 10.1046/j.1432-1327.1999.00973.x. Eur J Biochem. 1999. PMID: 10583414
High-throughput NMR-based screening with competition binding experiments.
Dalvit C, Flocco M, Knapp S, Mostardini M, Perego R, Stockman BJ, Veronesi M, Varasi M. Dalvit C, et al. J Am Chem Soc. 2002 Jul 3;124(26):7702-9. doi: 10.1021/ja020174b. J Am Chem Soc. 2002. PMID: 12083923
Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays.
Troiani S, Lupi R, Perego R, Depaolini SR, Thieffine S, Bosotti R, Rusconi L. Troiani S, et al. FEBS J. 2011 Oct;278(19):3676-87. doi: 10.1111/j.1742-4658.2011.08286.x. Epub 2011 Sep 6. FEBS J. 2011. PMID: 21812934
Chemical and enzymatic treatment of endothelin.
Perego R, Gozzini L, Arlandini E, Bolis G, de Castiglione R. Perego R, et al. Int J Pept Protein Res. 1995 Nov;46(5):341-5. doi: 10.1111/j.1399-3011.1995.tb01066.x. Int J Pept Protein Res. 1995. PMID: 8567176
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