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Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response.
Pereira FV, Melo ACL, Low JS, de Castro ÍA, Braga TT, Almeida DC, Batista de Lima AGU, Hiyane MI, Correa-Costa M, Andrade-Oliveira V, Origassa CST, Pereira RM, Kaech SM, Rodrigues EG, Câmara NOS. Pereira FV, et al. Among authors: pereira rm. Oncotarget. 2018 May 25;9(40):25808-25825. doi: 10.18632/oncotarget.25380. eCollection 2018 May 25. Oncotarget. 2018. PMID: 29899823 Free PMC article.
Anti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10.
de Melo FM, Braga CJ, Pereira FV, Maricato JT, Origassa CS, Souza MF, Melo AC, Silva P, Tomaz SL, Gimenes KP, Scutti JA, Juliano MA, Zamboni DS, Câmara NO, Travassos LR, Ferreira LC, Rodrigues EG. de Melo FM, et al. Among authors: pereira fv. Immunol Cell Biol. 2015 Jan;93(1):86-98. doi: 10.1038/icb.2014.74. Epub 2014 Sep 16. Immunol Cell Biol. 2015. PMID: 25223833
Interleukin-6 and the Gut Microbiota Influence Melanoma Progression in Obese Mice.
Pereira FV, Melo ACL, Silva MB, de Melo FM, Terra FF, Castro IA, Perandini LA, Miyagi MT, Sato FT, Origassa CST, Hiyane MI, Donato J Jr, Wasinski F, Araujo RC, Festuccia WTL, da Silva JS, Camara NOS. Pereira FV, et al. Nutr Cancer. 2021;73(4):642-651. doi: 10.1080/01635581.2020.1764982. Epub 2020 May 14. Nutr Cancer. 2021. PMID: 32406264
TLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models.
Pereira FV, Melo AC, de Melo FM, Mourão-Sá D, Silva P, Berzaghi R, Herbozo CC, Coelho-Dos-Reis J, Scutti JA, Origassa CS, Pereira RM, Juliano L, Juliano MA, Carmona AK, Câmara NO, Tsuji M, Travassos LR, Rodrigues EG. Pereira FV, et al. Among authors: pereira rm. Oncoimmunology. 2016 May 5;5(7):e1178420. doi: 10.1080/2162402X.2016.1178420. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622031 Free PMC article.
β-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma.
Arruda DC, Santos LC, Melo FM, Pereira FV, Figueiredo CR, Matsuo AL, Mortara RA, Juliano MA, Rodrigues EG, Dobroff AS, Polonelli L, Travassos LR. Arruda DC, et al. Among authors: pereira fv. J Biol Chem. 2012 Apr 27;287(18):14912-22. doi: 10.1074/jbc.M111.322362. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334655 Free PMC article.
Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo.
Figueiredo CR, Matsuo AL, Pereira FV, Rabaça AN, Farias CF, Girola N, Massaoka MH, Azevedo RA, Scutti JA, Arruda DC, Silva LP, Rodrigues EG, Lago JH, Travassos LR, Silva RM. Figueiredo CR, et al. Among authors: pereira fv. Pharmacogn Mag. 2014 Apr;10(Suppl 2):S363-76. doi: 10.4103/0973-1296.133284. Pharmacogn Mag. 2014. PMID: 24991116 Free PMC article.
A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies.
Pereira FV, Ferreira-Guimarães CA, Paschoalin T, Scutti JA, Melo FM, Silva LS, Melo AC, Silva P, Tiago M, Matsuo AL, Juliano L, Juliano MA, Carmona AK, Travassos LR, Rodrigues EG. Pereira FV, et al. PLoS One. 2014 Apr 30;9(4):e96141. doi: 10.1371/journal.pone.0096141. eCollection 2014. PLoS One. 2014. PMID: 24788523 Free PMC article.
64 results