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Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming.
Ford DJ, Duggan NM, Fry SE, Ripoll-Rozada J, Agten SM, Liu W, Corcilius L, Hackeng TM, van Oerle R, Spronk HMH, Ashhurst AS, Mini Sasi V, Kaczmarski JA, Jackson CJ, Pereira PJB, Passioura T, Suga H, Payne RJ. Ford DJ, et al. Among authors: pereira pjb. J Med Chem. 2021 Jun 10;64(11):7853-7876. doi: 10.1021/acs.jmedchem.1c00651. Epub 2021 May 27. J Med Chem. 2021. PMID: 34044534
Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.
Pirone L, Ripoll-Rozada J, Leone M, Ronca R, Lombardo F, Fiorentino G, Andersen JF, Pereira PJB, Arcà B, Pedone E. Pirone L, et al. Among authors: pereira pjb. J Biol Chem. 2017 Jul 28;292(30):12632-12642. doi: 10.1074/jbc.M117.788042. Epub 2017 Jun 7. J Biol Chem. 2017. PMID: 28592490 Free PMC article.
Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics.
Watson EE, Liu X, Thompson RE, Ripoll-Rozada J, Wu M, Alwis I, Gori A, Loh CT, Parker BL, Otting G, Jackson S, Pereira PJB, Payne RJ. Watson EE, et al. Among authors: pereira pjb. ACS Cent Sci. 2018 Apr 25;4(4):468-476. doi: 10.1021/acscentsci.7b00612. Epub 2018 Mar 28. ACS Cent Sci. 2018. PMID: 29721529 Free PMC article.
Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides.
Ripoll-Rozada J, Costa M, Manso JA, Maranha A, Miranda V, Sequeira A, Ventura MR, Macedo-Ribeiro S, Pereira PJB, Empadinhas N. Ripoll-Rozada J, et al. Among authors: pereira pjb. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):835-844. doi: 10.1073/pnas.1813450116. Epub 2019 Jan 3. Proc Natl Acad Sci U S A. 2019. PMID: 30606802 Free PMC article.
A simple linearization method unveils hidden enzymatic assay interferences.
Pinto MF, Ripoll-Rozada J, Ramos H, Watson EE, Franck C, Payne RJ, Saraiva L, Pereira PJB, Pastore A, Rocha F, Martins PM. Pinto MF, et al. Among authors: pereira pjb. Biophys Chem. 2019 Sep;252:106193. doi: 10.1016/j.bpc.2019.106193. Epub 2019 May 29. Biophys Chem. 2019. PMID: 31195341
Rapid assembly and profiling of an anticoagulant sulfoprotein library.
Watson EE, Ripoll-Rozada J, Lee AC, Wu MCL, Franck C, Pasch T, Premdjee B, Sayers J, Pinto MF, Martins PM, Jackson SP, Pereira PJB, Payne RJ. Watson EE, et al. Among authors: pereira pjb. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13873-13878. doi: 10.1073/pnas.1905177116. Epub 2019 Jun 20. Proc Natl Acad Sci U S A. 2019. PMID: 31221752 Free PMC article.
73 results