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Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood.
Hui H, Perfetti R. Hui H, et al. Among authors: perfetti r. Eur J Endocrinol. 2002 Feb;146(2):129-41. doi: 10.1530/eje.0.1460129. Eur J Endocrinol. 2002. PMID: 11834421 Review.
Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion.
Noushmehr H, D'Amico E, Farilla L, Hui H, Wawrowsky KA, Mlynarski W, Doria A, Abumrad NA, Perfetti R. Noushmehr H, et al. Among authors: perfetti r. Diabetes. 2005 Feb;54(2):472-81. doi: 10.2337/diabetes.54.2.472. Diabetes. 2005. PMID: 15677505
The contribution of gene profile analysis to the design of a molecular approach to treat diabetes in humans.
Perfetti R, D'Amico E. Perfetti R, et al. Diabetes Technol Ther. 2003;5(3):421-3. doi: 10.1089/152091503765691929. Diabetes Technol Ther. 2003. PMID: 12828826 No abstract available.
Insulin and glucose regulate the expression of the DNA repair enzyme XPD.
Merkel P, Khoury N, Bertolotto C, Perfetti R. Merkel P, et al. Among authors: perfetti r. Mol Cell Endocrinol. 2003 Mar 28;201(1-2):75-85. doi: 10.1016/s0303-7207(02)00432-x. Mol Cell Endocrinol. 2003. PMID: 12706296
GLP-1 stimulates glucose-derived de novo fatty acid synthesis and chain elongation during cell differentiation and insulin release.
Bulotta A, Perfetti R, Hui H, Boros LG. Bulotta A, et al. Among authors: perfetti r. J Lipid Res. 2003 Aug;44(8):1559-65. doi: 10.1194/jlr.M300093-JLR200. Epub 2003 Jun 1. J Lipid Res. 2003. PMID: 12777469
Structure and function studies of glucagon-like peptide-1 (GLP-1): the designing of a novel pharmacological agent for the treatment of diabetes.
Hui H, Zhao X, Perfetti R. Hui H, et al. Among authors: perfetti r. Diabetes Metab Res Rev. 2005 Jul-Aug;21(4):313-31. doi: 10.1002/dmrr.553. Diabetes Metab Res Rev. 2005. PMID: 15852457 Review.
Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs.
D'Amico E, Hui H, Khoury N, Di Mario U, Perfetti R. D'Amico E, et al. Among authors: perfetti r. J Mol Endocrinol. 2005 Apr;34(2):377-90. doi: 10.1677/jme.1.01655. J Mol Endocrinol. 2005. PMID: 15821104
Adenovirus-mediated XIAP gene transfer reverses the negative effects of immunosuppressive drugs on insulin secretion and cell viability of isolated human islets.
Hui H, Khoury N, Zhao X, Balkir L, D'Amico E, Bullotta A, Nguyen ED, Gambotto A, Perfetti R. Hui H, et al. Among authors: perfetti r. Diabetes. 2005 Feb;54(2):424-33. doi: 10.2337/diabetes.54.2.424. Diabetes. 2005. PMID: 15677500
Gene expression profiling of cultured human islet preparations.
Hui H, Wang C, Li H, Bulotta A, D'Amico E, Khoury N, Nguyen E, Di Mario U, Chen IY, Perfetti R. Hui H, et al. Among authors: perfetti r. Diabetes Technol Ther. 2004 Aug;6(4):481-92. doi: 10.1089/1520915041705866. Diabetes Technol Ther. 2004. PMID: 15321003
The role of GLP-1 in the regulation of islet cell mass.
Bulotta A, Farilla L, Hui H, Perfetti R. Bulotta A, et al. Among authors: perfetti r. Cell Biochem Biophys. 2004;40(3 Suppl):65-78. doi: 10.1385/cbb:40:3:65. Cell Biochem Biophys. 2004. PMID: 15289644 Review.
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