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Perfluoroalkylated substances (PFAS) affect oxidative stress biomarkers in vitro.
Wielsøe M, Long M, Ghisari M, Bonefeld-Jørgensen EC. Wielsøe M, et al. Chemosphere. 2015 Jun;129:239-45. doi: 10.1016/j.chemosphere.2014.10.014. Epub 2014 Nov 12. Chemosphere. 2015. PMID: 25455676
Perfluoroalkylated substances (PFAS) have been widely used since 1950s and humans are exposed through food, drinking water, consumer products, dust, etc. The long-chained PFAS are persistent in the environment and accumulate in wildlife and humans. The
Perfluoroalkylated substances (PFAS) have been widely used since 1950s and humans are exposed through food, drinking wa
Combined toxicity of polystyrene microplastics and perfluorobutane sulfonate on mouse liver: Impact on lipid metabolism and gut-liver axis disruption.
Jiang M, Li X, Cai C, Xu Y, Song P, Yu J. Jiang M, et al. Ecotoxicol Environ Saf. 2025 Mar 1;292:117904. doi: 10.1016/j.ecoenv.2025.117904. Epub 2025 Feb 20. Ecotoxicol Environ Saf. 2025. PMID: 39983513 Free article.
Microplastics (MPs) in the environment can adsorb perfluoroalkyl substance (PFAS), leading to combined toxicity in various organisms. Most researches have focused on single-exposure effects on mouse liver, with limited studies on the mechanisms behind the com …
Microplastics (MPs) in the environment can adsorb perfluoroalkyl substance (PFAS), leading to combined toxicity in vari …
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua).
Dale K, Yadetie F, Müller MB, Pampanin DM, Gilabert A, Zhang X, Tairova Z, Haarr A, Lille-Langøy R, Lyche JL, Porte C, Karlsen OA, Goksøyr A. Dale K, et al. Aquat Toxicol. 2020 Oct;227:105590. doi: 10.1016/j.aquatox.2020.105590. Epub 2020 Aug 11. Aquat Toxicol. 2020. PMID: 32891021 Free article.
The hepatosomatic index (HSI) was significantly reduced for three of the combined PAH/PFAS exposure groups (L-PAH/H-PFAS, H-PAH/L-PFAS, H-PAH/H-PFAS). Analysis of the hepatic proteome identified that pathways related to lipid degradation were significa …
The hepatosomatic index (HSI) was significantly reduced for three of the combined PAH/PFAS exposure groups (L-PAH/H-PFAS, H-PA …
Molecular impacts of perfluorinated chemicals (PFASs) in the liver and testis of male largemouth bass (Micropterus salmoides) in Minnesota Lakes.
Collí-Dulá RC, Martyniuk CJ, Streets S, Denslow ND, Lehr R. Collí-Dulá RC, et al. Comp Biochem Physiol Part D Genomics Proteomics. 2016 Sep;19:129-139. doi: 10.1016/j.cbd.2016.02.001. Epub 2016 Feb 6. Comp Biochem Physiol Part D Genomics Proteomics. 2016. PMID: 26907229
Largemouth bass with high PFAS concentrations exhibited changes in the expression of genes related to lipid metabolism, energy production, RNA processing, protein production/degradation and contaminant detoxification, all of which are consistent with biomarker respo …
Largemouth bass with high PFAS concentrations exhibited changes in the expression of genes related to lipid metabolism, energy produc …
Lower toxicity of HFPO-DA compared to its predecessor PFOA to the earthworm Eisenia fetida: Evidence from oxidative stress and transcriptomic analysis.
Wu R, Wang X, Zhang J, Lu C, Li B, Du Z, Wang J, Wang J, Yang Y, Zhu L. Wu R, et al. J Hazard Mater. 2025 Mar 15;486:137003. doi: 10.1016/j.jhazmat.2024.137003. Epub 2024 Dec 24. J Hazard Mater. 2025. PMID: 39724713
Hexafluoropropylene oxide dimer acid (HFPO-DA), an emerging perfluoroalkyl substance (PFAS) that is replacing traditional PFASs, has a wide range of industrial applications and has been detected globally in the environment. ...Our findings revealed that both …
Hexafluoropropylene oxide dimer acid (HFPO-DA), an emerging perfluoroalkyl substance (PFAS) that is replacing tradition …