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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r).
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Liu JP, et al. Among authors: perkins as. Cell. 1993 Oct 8;75(1):59-72. Cell. 1993. PMID: 8402901
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.
Brannan CI, Perkins AS, Vogel KS, Ratner N, Nordlund ML, Reid SW, Buchberg AM, Jenkins NA, Parada LF, Copeland NG. Brannan CI, et al. Among authors: perkins as. Genes Dev. 1994 May 1;8(9):1019-29. doi: 10.1101/gad.8.9.1019. Genes Dev. 1994. PMID: 7926784
Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.
Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF. Stanton BR, et al. Among authors: perkins as. Genes Dev. 1992 Dec;6(12A):2235-47. doi: 10.1101/gad.6.12a.2235. Genes Dev. 1992. PMID: 1459449
Molecular regulation of myelopoiesis.
Wolff L, Perkins AS. Wolff L, et al. Among authors: perkins as. Trends Cell Biol. 1995 Sep;5(9):369-71. doi: 10.1016/s0962-8924(00)89072-8. Trends Cell Biol. 1995. PMID: 14732081 No abstract available.
Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.
Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, Jenkins NA, Copeland NG. Bard-Chapeau EA, et al. Among authors: perkins as. PLoS One. 2014 Feb 27;9(2):e89397. doi: 10.1371/journal.pone.0089397. eCollection 2014. PLoS One. 2014. PMID: 24586749 Free PMC article.
Transduction of the human insulin gene via retroviral vectors fails to yield spliced transcripts.
Perkins AS, Kirschmeier PT, Weinstein IB. Perkins AS, et al. DNA. 1989 Jan-Feb;8(1):59-68. doi: 10.1089/dna.1.1989.8.59. DNA. 1989. PMID: 2468464
Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development.
Perkins AS, Mercer JA, Jenkins NA, Copeland NG. Perkins AS, et al. Development. 1991 Feb;111(2):479-87. Development. 1991. PMID: 1893871
PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.
Zhang Y, Stehling-Sun S, Lezon-Geyda K, Juneja SC, Coillard L, Chatterjee G, Wuertzer CA, Camargo F, Perkins AS. Zhang Y, et al. Among authors: perkins as. Blood. 2011 Oct 6;118(14):3853-61. doi: 10.1182/blood-2011-02-334680. Epub 2011 Jun 10. Blood. 2011. PMID: 21666053 Free PMC article.
Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library.
Ma X, Husain T, Peng H, Lin S, Mironenko O, Maun N, Johnson S, Tuck D, Berliner N, Krause DS, Perkins AS. Ma X, et al. Among authors: perkins as. Blood. 2002 Aug 1;100(3):833-44. doi: 10.1182/blood.v100.3.833. Blood. 2002. PMID: 12130493
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, Zhang Y, Perkins AS, Shannon K, Hemann MT, Puissant A, Stegmaier K. Fenouille N, et al. Among authors: perkins as. Nat Med. 2017 Mar;23(3):301-313. doi: 10.1038/nm.4283. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191887 Free PMC article.
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