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Studies of the paradoxical effect of caspofungin at high drug concentrations.
Stevens DA, White TC, Perlin DS, Selitrennikoff CP. Stevens DA, et al. Diagn Microbiol Infect Dis. 2005 Mar;51(3):173-8. doi: 10.1016/j.diagmicrobio.2004.10.006. Diagn Microbiol Infect Dis. 2005. PMID: 15766602
Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.
Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E, Li W, Vyas V, Fan H, Abruzzo G, Flattery A, Gill C, Chrebet G, Parent SA, Kurtz M, Teppler H, Douglas CM, Perlin DS. Park S, et al. Antimicrob Agents Chemother. 2005 Aug;49(8):3264-73. doi: 10.1128/AAC.49.8.3264-3273.2005. Antimicrob Agents Chemother. 2005. PMID: 16048935 Free PMC article. Clinical Trial.
Multicenter study of epidemiological cutoff values and detection of resistance in Candida spp. to anidulafungin, caspofungin, and micafungin using the Sensititre YeastOne colorimetric method.
Espinel-Ingroff A, Alvarez-Fernandez M, Cantón E, Carver PL, Chen SC, Eschenauer G, Getsinger DL, Gonzalez GM, Govender NP, Grancini A, Hanson KE, Kidd SE, Klinker K, Kubin CJ, Kus JV, Lockhart SR, Meletiadis J, Morris AJ, Pelaez T, Quindós G, Rodriguez-Iglesias M, Sánchez-Reus F, Shoham S, Wengenack NL, Borrell Solé N, Echeverria J, Esperalba J, Gómez-G de la Pedrosa E, García García I, Linares MJ, Marco F, Merino P, Pemán J, Pérez Del Molino L, Roselló Mayans E, Rubio Calvo C, Ruiz Pérez de Pipaon M, Yagüe G, Garcia-Effron G, Guinea J, Perlin DS, Sanguinetti M, Shields R, Turnidge J. Espinel-Ingroff A, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6725-32. doi: 10.1128/AAC.01250-15. Epub 2015 Aug 17. Antimicrob Agents Chemother. 2015. PMID: 26282428 Free PMC article.
Resistance to echinocandin-class antifungal drugs.
Perlin DS. Perlin DS. Drug Resist Updat. 2007 Jun;10(3):121-30. doi: 10.1016/j.drup.2007.04.002. Epub 2007 Jun 13. Drug Resist Updat. 2007. PMID: 17569573 Free PMC article. Review.
Current perspectives on echinocandin class drugs.
Perlin DS. Perlin DS. Future Microbiol. 2011 Apr;6(4):441-57. doi: 10.2217/fmb.11.19. Future Microbiol. 2011. PMID: 21526945 Free PMC article. Review.
Hematogenous infections due to Candida parapsilosis: changing trends in fungemic patients at a comprehensive cancer center during the last four decades.
Safdar A, Perlin DS, Armstrong D. Safdar A, et al. Diagn Microbiol Infect Dis. 2002 Sep;44(1):11-6. doi: 10.1016/s0732-8893(02)00423-6. Diagn Microbiol Infect Dis. 2002. PMID: 12376025
CD101: a novel long-acting echinocandin.
Zhao Y, Perez WB, Jiménez-Ortigosa C, Hough G, Locke JB, Ong V, Bartizal K, Perlin DS. Zhao Y, et al. Cell Microbiol. 2016 Sep;18(9):1308-16. doi: 10.1111/cmi.12640. Epub 2016 Jul 22. Cell Microbiol. 2016. PMID: 27354115 Free PMC article.
Dose escalation studies with caspofungin against Candida glabrata.
Domán M, Kovács R, Perlin DS, Kardos G, Gesztelyi R, Juhász B, Bozó A, Majoros L. Domán M, et al. J Med Microbiol. 2015 Sep;64(9):998-1007. doi: 10.1099/jmm.0.000116. Epub 2015 Jun 30. J Med Microbiol. 2015. PMID: 26296340 Free PMC article.
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