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Resistance to echinocandin-class antifungal drugs.
Perlin DS. Perlin DS. Drug Resist Updat. 2007 Jun;10(3):121-30. doi: 10.1016/j.drup.2007.04.002. Epub 2007 Jun 13. Drug Resist Updat. 2007. PMID: 17569573 Free PMC article. Review.
Cloning and characterization of the plasma membrane H(+)-ATPase from Candida albicans.
Monk BC, Kurtz MB, Marrinan JA, Perlin DS. Monk BC, et al. J Bacteriol. 1991 Nov;173(21):6826-36. doi: 10.1128/jb.173.21.6826-6836.1991. J Bacteriol. 1991. PMID: 1834633 Free PMC article.
Defective H(+)-ATPase of hygromycin B-resistant pma1 mutants fromSaccharomyces cerevisiae.
Perlin DS, Harris SL, Seto-Young D, Haber JE. Perlin DS, et al. J Biol Chem. 1989 Dec 25;264(36):21857-64. J Biol Chem. 1989. PMID: 2532214
Mutations in the plasma membrane H(+)-ATPase gene (PMA1) of Saccharomyces cerevisiae that confer growth resistance to hygromycin B have been shown recently to cause a marked depolarization of whole cell membrane potential (Perlin, D. ...
Mutations in the plasma membrane H(+)-ATPase gene (PMA1) of Saccharomyces cerevisiae that confer growth resistance to hygromycin B have been …
The yeast plasma membrane proton pumping ATPase is a viable antifungal target. I. Effects of the cysteine-modifying reagent omeprazole.
Monk BC, Mason AB, Abramochkin G, Haber JE, Seto-Young D, Perlin DS. Monk BC, et al. Biochim Biophys Acta. 1995 Oct 4;1239(1):81-90. doi: 10.1016/0005-2736(95)00133-n. Biochim Biophys Acta. 1995. PMID: 7548148
Exploring an antifungal target in the plasma membrane H(+)-ATPase of fungi.
Seto-Young D, Monk B, Mason AB, Perlin DS. Seto-Young D, et al. Biochim Biophys Acta. 1997 Jun 12;1326(2):249-56. doi: 10.1016/s0005-2736(97)00028-x. Biochim Biophys Acta. 1997. PMID: 9218555
The plasma membrane H(+)-ATPase of fungi. A candidate drug target?
Perlin DS, Seto-Young D, Monk BC. Perlin DS, et al. Ann N Y Acad Sci. 1997 Nov 3;834:609-17. doi: 10.1111/j.1749-6632.1997.tb52330.x. Ann N Y Acad Sci. 1997. PMID: 9405872 Review.
Antifungal activity of amphotericin B cochleates against Candida albicans infection in a mouse model.
Zarif L, Graybill JR, Perlin D, Najvar L, Bocanegra R, Mannino RJ. Zarif L, et al. Antimicrob Agents Chemother. 2000 Jun;44(6):1463-9. doi: 10.1128/aac.44.6.1463-1469.2000. Antimicrob Agents Chemother. 2000. PMID: 10817694 Free PMC article.
Molecular characterization of the plasma membrane H(+)-ATPase, an antifungal target in Cryptococcus neoformans.
Soteropoulos P, Vaz T, Santangelo R, Paderu P, Huang DY, Tamás MJ, Perlin DS. Soteropoulos P, et al. Antimicrob Agents Chemother. 2000 Sep;44(9):2349-55. doi: 10.1128/aac.44.9.2349-2355.2000. Antimicrob Agents Chemother. 2000. PMID: 10952578 Free PMC article.
Efficacy of oral cochleate-amphotericin B in a mouse model of systemic candidiasis.
Santangelo R, Paderu P, Delmas G, Chen ZW, Mannino R, Zarif L, Perlin DS. Santangelo R, et al. Antimicrob Agents Chemother. 2000 Sep;44(9):2356-60. doi: 10.1128/aac.44.9.2356-2360.2000. Antimicrob Agents Chemother. 2000. PMID: 10952579 Free PMC article.
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