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A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Kilpeläinen TO, Richard MA, Aslibekyan S, Bartz TM, Dorajoo R, Li C, Liu Y, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kammerer CM, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lee WJ, Lin KH, Luan J, Lyytikäinen LP, McKenzie CA, Nelson CP, Noordam R, Scott RA, Sheu WHH, Stančáková A, Takeuchi F, van der Most PJ, Varga TV, Waken RJ, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking DE, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cade B, Campbell A, Canouil M, Chakravarti A, Cocca M, Collins FS, Connell JM, de Mutsert R, de Silva HJ, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Forouhi NG, Franco OH, Friedlander Y, Gao H, Gigante B, Gu CC, Gupta P, H… See abstract for full author list ➔ Sung YJ, et al. Among authors: perls t. Hum Mol Genet. 2019 Aug 1;28(15):2615-2633. doi: 10.1093/hmg/ddz070. Hum Mol Genet. 2019. PMID: 31127295 Free PMC article.
Clustering by genetic ancestry using genome-wide SNP data.
Solovieff N, Hartley SW, Baldwin CT, Perls TT, Steinberg MH, Sebastiani P. Solovieff N, et al. Among authors: perls tt. BMC Genet. 2010 Dec 9;11:108. doi: 10.1186/1471-2156-11-108. BMC Genet. 2010. PMID: 21143920 Free PMC article.
Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).
An P, Miljkovic I, Thyagarajan B, Kraja AT, Daw EW, Pankow JS, Selvin E, Kao WH, Maruthur NM, Nalls MA, Liu Y, Harris TB, Lee JH, Borecki IB, Christensen K, Eckfeldt JH, Mayeux R, Perls TT, Newman AB, Province MA. An P, et al. Among authors: perls tt. Metabolism. 2014 Apr;63(4):461-8. doi: 10.1016/j.metabol.2013.11.018. Epub 2013 Dec 4. Metabolism. 2014. PMID: 24405752 Free PMC article.
Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
Lee JH, Cheng R, Honig LS, Feitosa M, Kammerer CM, Kang MS, Schupf N, Lin SJ, Sanders JL, Bae H, Druley T, Perls T, Christensen K, Province M, Mayeux R. Lee JH, et al. Among authors: perls t. Front Genet. 2014 Jan 17;4:310. doi: 10.3389/fgene.2013.00310. eCollection 2013. Front Genet. 2014. PMID: 24478790 Free PMC article.
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. Broer L, et al. Among authors: perls tt. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8. doi: 10.1093/gerona/glu166. Epub 2014 Sep 8. J Gerontol A Biol Sci Med Sci. 2015. PMID: 25199915 Free PMC article.
Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index.
Minster RL, Sanders JL, Singh J, Kammerer CM, Barmada MM, Matteini AM, Zhang Q, Wojczynski MK, Daw EW, Brody JA, Arnold AM, Lunetta KL, Murabito JM, Christensen K, Perls TT, Province MA, Newman AB. Minster RL, et al. Among authors: perls tt. J Gerontol A Biol Sci Med Sci. 2015 Aug;70(8):1003-8. doi: 10.1093/gerona/glv006. Epub 2015 Mar 10. J Gerontol A Biol Sci Med Sci. 2015. PMID: 25758594 Free PMC article.
Heritability of telomere length in a study of long-lived families.
Honig LS, Kang MS, Cheng R, Eckfeldt JH, Thyagarajan B, Leiendecker-Foster C, Province MA, Sanders JL, Perls T, Christensen K, Lee JH, Mayeux R, Schupf N. Honig LS, et al. Among authors: perls t. Neurobiol Aging. 2015 Oct;36(10):2785-90. doi: 10.1016/j.neurobiolaging.2015.06.017. Epub 2015 Jun 18. Neurobiol Aging. 2015. PMID: 26239175 Free PMC article.
182 results